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Invitrogen™ UGGT1 Polyclonal Antibody, Invitrogen™
Rabbit Polyclonal Antibody
Marca: Invitrogen™ PA5145406
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Descripción
UDP-glucose:glycoprotein glucosyltransferase (UGGT) is a 170 kDa lumenal endoplasmic reticulum (ER) resident protein that catalyzes monoglucosylation of high mannose oligosaccharides. UGGT catalyzes the transfer of glucose from UDP-glucose to Man7-9GlcNAc2-moiety of unfolded glycoproteins in a Ca2+ dependent reaction. UGGT binds unfolded glycoprotein via two elements on its substrate: a N-acetylglucosamine unit on the oligosaccharide and hydrophobic amino acids that are exposed in the denatured conformation. It is postulated that UGGT serves as a sensor that is able to distinguish between folded and denatured protein in the ER.
Especificaciones
| UGGT1 | |
| Polyclonal | |
| Unconjugated | |
| Uggt1 | |
| 0910001L17Rik; A930007H10Rik; AA589501; AI414429; AI448372; C820010P03Rik; Gt; HUGT1; RUGT; rUGT1; UDP--Glc:glycoprotein glucosyltransferase; UDP-glucose ceramide glucosyltransferase-like 1; UDP-glucose glycoprotein glucosyltransferase 1; UDP-glucose glycoprotein: glucosyltransferase UGGT; UDP-glucose:glycoprotein glucosyltransferase; UDP-glucose:glycoprotein glucosyltransferase 1; UGCGL1; Uggt; Uggt1; Ugt1; Ugtr | |
| Rabbit | |
| Antigen affinity chromatography, Protein A | |
| RUO | |
| 100155117, 56886 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Liquid |
| Western Blot | |
| 0.5 mg/mL | |
| PBS with 50% glycerol and 0.05% Proclin 300; pH 7.4 | |
| Q9NYU2 | |
| Uggt1 | |
| Recombinant Human UGGT1 protein, Leu1221-Leu1536 (Accession #Q9NYU2). | |
| 20 μL | |
| Primary | |
| Human, Pig | |
| Antibody | |
| IgG |
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