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Descripción
This antibody detects 70kD band of UBQLN1.
PLIC1 is an ubiquitin-like protein (ubiquilin) that shares high degree of similarity with related products in yeast, rat and frog. Ubiquilins contain a N-terminal ubiquitin-like domain and a C-terminal ubiquitin-associated domain. They physically associate with both proteasomes and ubiquitin ligases, and thus are thought to functionally link the ubiquitination machinery to the proteasome to affect in vivo protein degradation. This ubiquilin has also been shown to modulate accumulation of presenilin proteins, and is found in lesions associated with Alzheimer′s and Parkinson′s disease.
Especificaciones
Especificaciones
| Antígeno | Ubiquilin 1 |
| Aplicaciones | Immunofluorescence, Western Blot, Immunocytochemistry |
| Clasificación | Polyclonal |
| Concentración | 0.16 mg/mL |
| Conjugado | Unconjugated |
| Formulación | PBS with 50% glycerol and 0.02% sodium azide; pH 7.3 |
| génica | UBQLN1 |
| N.º de referencia del gen | Q9JJP9, Q9UMX0 |
| Alias de gen | DA41, DSK2, hPLIC 1, PLIC 1, PLIC1, ubiquilin 1, UBQLN1, XDRP1 |
| Símbolos de los genes | Ubqln1 |
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Título del producto
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