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Invitrogen™ TWIST1 Polyclonal Antibody, APC
Sheep Polyclonal Antibody
Marca: Invitrogen™ PA546902
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Descripción
In direct ELISAs, less than 16% cross-reactivity with recombinant human Twist-2 is observed.
TWIST1 acts as a transcriptional regulator. It inhibits myogensis by sequestering E proteins, inhibiting trans-activation by MEF2, and inhibiting DNA-binding by MYOD1 through physical interaction. TWIST1 also represses proinflammatory cytokines such as TNFA and IL1B. TWIST also regulates cranial suture patterning and fusion and gene expression differentially depending on dimer composition. Mutations in the gene are implicated in Saethre-Chotzen syndrome, a disease characterized by coronal synostosis, brachycephaly, low front hairline, facial asymmetry, hypertelorism, broad halluces, and clinodactyly.
Especificaciones
| TWIST1 | |
| Polyclonal | |
| Buffered saline solution with BSA and 0.09% sodium azide | |
| Q15672 | |
| TWIST1 | |
| E. coli-derived recombinant human Twist-1 Met1-His202. | |
| 100 Tests | |
| Primary | |
| Human | |
| Antibody | |
| IgG |
| Flow Cytometry | |
| APC | |
| TWIST1 | |
| AA960487; ACS3; B-HLH DNA binding protein; bHLHa38; BPES2; BPES3; charlie chaplin; class A basic helix-loop-helix protein 38; CRS; CRS1; CSO; H-twist; M-twist; p ACS3; Pde; pdt; Pluridigite; polydactyly EMS; SCS; Ska>m10Jus>; Ska>sup>m10Jus>/sup>; Ska10; Twist; twist basic helix-loop-helix transcription factor 1; twist family bHLH transcription factor 1; twist gene homolog 1; twist homolog 1; TWIST homolog of drosophila; Twist1; twist-related protein 1 | |
| Sheep | |
| Antigen affinity chromatography | |
| RUO | |
| 7291 | |
| 4°C, store in dark, DO NOT FREEZE! | |
| Liquid |
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