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PeproTech TWEAK Polyclonal Antibody, Biotin, PeproTech®, Invitrogen™
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Código de producto. 17843893
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Cantidad:
2 x 500 μg
25 μg
50 μg
500 μg
Tamaño de la unidad:
1 miligramo
25 microgramos
50 microgramos
500 microgramos
Código de producto. Cantidad unitSize
17843893 50 μg 50 microgramos
17803963 25 μg 25 microgramos
17844333 2 x 500 μg 1 miligramo
30054654 500 μg 500 microgramos
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Código de producto. 17843893

Marca: PeproTech 500P137GBT50UG

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Goat Polyclonal Antibody

AA Sequence of recombinant protein: MKGRKTRARR AIAAHYEVHP RPGQDGAQAG VDGTVSGWEE ARINSSSPLR YNRQIGEFIV TRAGLYYLYC QVHFDEGKAV YLKLDLLVDG VLALRCLEEF SATAASSLGP QLRLCQVSGL LALRPGSSLR IRTLPWAHLK AAPFLTYFGL FQVH. Preparation: Produced from sera of goats immunized with highly pure Recombinant Human TWEAK. Anti-Human TWEAK-specific antibody was purified by affinity chromatography and then biotinylated. Sandwich ELISA: To detect Human TWEAK by sandwich ELISA (using 100 μL/well antibody solution) a concentration of 0.25-1.0 μg/mL of this antibody is required. This biotinylated polyclonal antibody, in conjunction with PeproTech Polyclonal Anti-Human TWEAK (500-P137G) as a capture antibody, allows the detection of at least 0.2-0.4 ng/well of Recombinant Human TWEAK. Western Blot: To detect hTWEAK by Western Blot analysis this antibody can be used at a concentration of 0.1-0.2 μg/mL. Used in conjunction with compatible secondary reagents the detection limit for Recombinant hTWEAK is 1.5-3.0 ng/lane, under either reducing or non-reducing conditions. 500-P137GBT-1MG will be provided as 2 x 500 μg

TNF-related weak inducer of apoptosis (TWEAK) is a member of the tumor necrosis factor superfamily (TNFSF) of structurally related cytokines. Like most other members of this family, TWEAK is a cell surface-associated type II transmembrane protein although a smaller, biologically active form can also be generated by cleavage near the cell membrane. TWEAK has multiple biological activities, including stimulation of cell growth and angiogenesis, induction of inflammatory cytokines, in addition to stimulation of apoptosis. The TWEAK signal transduction pathway has not been well established but it appears to signal via TweakR/Fn14 in a manner similar to that described for other TNFSF members that bind receptors lacking death domains.
TRUSTED_SUSTAINABILITY

Especificaciones

Antígeno TWEAK
Aplicaciones ELISA, Western Blot
Clasificación Polyclonal
Concentración 0.1-1.0 mg/mL
Conjugado Biotin
Formulación PBS with no preservative
génica Tnfsf12
N.º de referencia del gen O43508
Alias de gen APO3 ligand; APO3/DR3 ligand; APO3L; Dr3l; Dr3lg; LOW QUALITY PROTEIN: tumor necrosis factor ligand superfamily member 12; MGC129581; MGC20669; TNF superfamily member 12; TNF-related weak inducer of apoptosis; TNFSF12; TNLG4A; tumor necrosis factor (ligand) superfamily member 12; tumor necrosis factor (ligand) superfamily, member 12; tumor necrosis factor ligand 4A; tumor necrosis factor ligand superfamily member 12; Tumor necrosis factor ligand superfamily member 12, membrane form; Tumor necrosis factor ligand superfamily member 12, secreted form; tumor necrosis factor superfamily member 12; TWEAK; UNQ181/PRO207; zgc:153941
Símbolos de los genes Tnfsf12
Especie del huésped Goat
Inmunógeno E.coli-derived, 17.0 kDa Recombinant Human TWEAK.
Método de purificación Antigen affinity chromatography
Cantidad 50 μg
Estado normativo RUO
Primario o secundario Primary
ID de gen (Entrez) 8742
Especies diana Human
Contenido y almacenamiento -20°C
Tipo de producto Antibody
Formulario Lyophilized
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