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Invitrogen™ TWEAK Monoclonal Antibody (173830)
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Código de producto. 15563472
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Cantidad:
500 μg
Tamaño de la unidad:
500 microgramos
Código de producto. Cantidad unitSize
15563472 500 μg 500 microgramos
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Código de producto. 15563472

Marca: Invitrogen™ MA523783

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Mouse Monoclonal Antibody

In sandwich ELISAs, approximately 15% reactivity with recombinant mouse TWEAK is observed and no cross-reactivity with recombinant human (rh) BAFF, rhEDA-A2, rhLIGHT, rhFas Ligand, rhGITR Ligand, rhLT alpha 1 beta 2, rhLT alpha 2 beta 1, rhOX40 Ligand, rhTNF-alpha, rhTRANCE, rhTRAIL, rh4-1BB, or rhAPRIL is observed. Reconstitute at 0.5 mg/mL in sterile PBS.

TNF-related weak inducer of apoptosis (TWEAK) is a member of the tumor necrosis factor superfamily (TNFSF) of structurally related cytokines. Like most other members of this family, TWEAK is a cell surface-associated type II transmembrane protein although a smaller, biologically active form can also be generated by cleavage near the cell membrane. TWEAK has multiple biological activities, including stimulation of cell growth and angiogenesis, induction of inflammatory cytokines, in addition to stimulation of apoptosis. The TWEAK signal transduction pathway has not been well established but it appears to signal via TweakR/Fn14 in a manner similar to that described for other TNFSF members that bind receptors lacking death domains.
TRUSTED_SUSTAINABILITY

Especificaciones

Antígeno TWEAK
Aplicaciones ELISA
Clasificación Monoclonal
Clon 173830
Concentración 0.5 mg/mL
Conjugado Unconjugated
Formulación PBS with 5% trehalose and No Preservative
génica Tnfsf12
N.º de referencia del gen O43508
Alias de gen APO3 ligand; APO3/DR3 ligand; APO3L; Dr3l; Dr3lg; LOW QUALITY PROTEIN: tumor necrosis factor ligand superfamily member 12; MGC129581; MGC20669; TNF superfamily member 12; TNF-related weak inducer of apoptosis; TNFSF12; TNLG4A; tumor necrosis factor (ligand) superfamily member 12; tumor necrosis factor (ligand) superfamily, member 12; tumor necrosis factor ligand 4A; tumor necrosis factor ligand superfamily member 12; Tumor necrosis factor ligand superfamily member 12, membrane form; Tumor necrosis factor ligand superfamily member 12, secreted form; tumor necrosis factor superfamily member 12; TWEAK; UNQ181/PRO207; zgc:153941
Símbolos de los genes Tnfsf12
Especie del huésped Mouse
Inmunógeno E. coli-derived recombinant human TWEAK/TNFSF12 Arg93-His249.
Método de purificación Protein A/G
Cantidad 500 μg
Estado normativo RUO
Primario o secundario Primary
ID de gen (Entrez) 8742
Especies diana Human
Contenido y almacenamiento -20°C, Avoid Freeze/Thaw Cycles
Tipo de producto Antibody
Formulario Lyophilized
Isotype IgG1
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