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Invitrogen™ TRPA1 Polyclonal Antibody

Código de producto. 17147253
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Cantidad:
100 μL
Tamaño de la unidad:
100 microlitros
Código de producto. Cantidad unitSize
17147253 100 μL 100 microlitros
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Código de producto. 17147253

Marca: Invitrogen™ PA5109320

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Descripción

Rabbit Polyclonal Antibody

Positive Control: L929, MG-63, NIH-3T3, rat brain tissue, human skin tissue, human esophagus tissue, mouse colon tissue.

TRPA1 is a TRP-related channel that responds to cold temperatures and pungent compounds and plays a role in both nociceptor and hair cell transduction. TRPA1 is a transformation -associated gene product in lung epithelia, whereas its protein distribution is primarily restricted to sensory neurons. Blocking TRPA1 may be a therapeutic target for treating cold hyperalgesia caused by inflammation and nerve damage. It is now known that TRPA1 protein is also widely expressed outside of the CNS and is dys-regulated during oncogenic transformation. The structure of TRPA1 is highly related to both the protein ankyrin and transmembrane proteins. The specific function of TRPA1 has not yet been determined; however, studies indicate the function may involve a role in signal transduction and growth control.
TRUSTED_SUSTAINABILITY

Especificaciones

Antígeno TRPA1
Aplicaciones Western Blot
Clasificación Polyclonal
Concentración 1 mg/mL
Conjugado Unconjugated
Formulación PBS with 0.2% BSA, 50% glycerol and 0.05% sodium azide; pH 7.4
génica Trpa1
N.º de referencia del gen O75762
Alias de gen Anktm1; ankyrin-like with transmembrane domains 1; ankyrin-like with transmembrane domains protein 1; FEPS; ion channel; drTRPA1; nompC; transformation-sensitive protein p120; transient receptor potential A1; transient receptor potential ankyrin 1a; transient receptor potential cation channel subfamily A member 1; transient receptor potential cation channel subfamily A member 1a; transient receptor potential cation channel, subfamily A, member 1a; transient receptor potential cation channel subfamily A member 1-like; transient receptor potential cation channel, subfamily A, member 1; transient receptor potential cation channel, subfamily A, member 1 L homeolog; transient receptor potential cation channel, subfamily A, member 1a; TRPA1; TRPA-1; trpa1.L; trpa1a; TRPA1b; XELAEV_18003616mg
Símbolos de los genes Trpa1
Especie del huésped Rabbit
Inmunógeno Recombinant protein within Human TRPA1 aa 505-755.
Método de purificación Affinity chromatography
Cantidad 100 μL
Estado normativo RUO
Primario o secundario Primary
ID de gen (Entrez) 8989
Especies diana Human
Contenido y almacenamiento -20°C, Avoid Freeze/Thaw Cycles, store in dark
Tipo de producto Antibody
Formulario Liquid
Isotype IgG
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