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Invitrogen™ TRK fused gene Polyclonal Antibody

Descripción
Immunogen sequence: LRRELIELRNK VNRLLDSLEP PGEPGPSTNI PENDTVDGRE EKSASDSSGK QSTQVMAASM SAFDPLKNQD EINKNVMSAF GLTDDQVSGP PS Highest antigen sequence identity to the following orthologs - mouse 96%, rat 97%.
TFG protein, a recently identified novel protein, is a human homolog of mouse TFG protein. It contains an N-terminal coiled-coil structure, a SPYGQ-rich region followed by octicosapeptide repeats. Research shows that TFG can modulate SHP-1 activity and is a novel member of the NF-kB pathway. The physiological functions of this protein remain largely elusive, but TFG is thought to function by associating with other proteins, including TANK and NEMO. TFG was first identified as a partner of NTRK1 and is involved in generating the thyroid TRK-T3 oncogene, as well as oncogenic rearrangements with ALK in anaplastic lymphoma and NOR1 in mixoid chondrosarcoma.
Especificaciones
Especificaciones
| Antígeno | TRK fused gene |
| Aplicaciones | Western Blot, Immunocytochemistry |
| Clasificación | Polyclonal |
| Concentración | 0.2 mg/mL |
| Conjugado | Unconjugated |
| Formulación | PBS with 40% glycerol and 0.02% sodium azide; pH 7.2 |
| génica | TFG |
| N.º de referencia del gen | Q92734 |
| Alias de gen | AI173908; HMSNP; protein TFG; SPG57; TF6; TFG; Trk-fused gene; TRK-fused gene protein; TRKT3; TRKT3 oncogene |
| Símbolos de los genes | TFG |
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Título del producto
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