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Invitrogen™ TRAF4 Polyclonal Antibody

Código de producto. 16364375 Tienda Thermo Scientific Productos
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Cantidad:
100 μg
Tamaño de la unidad:
100 microgramos
Código de producto. Cantidad unitSize
16364375 100 μg 100 microgramos
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Código de producto. 16364375

Marca: Invitrogen™ PA595106

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Rabbit Polyclonal Antibody

Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 μg/mL. Positive Control - WB: Rat Thymus Tissue, HELA Cell, JURKAT Cell, HEPA Cell. IHC: Rat Lymphonodus Tissue, Human Lung Cancer Tissue. Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

The tumor necrosis factor (TNF) receptor superfamily is composed of several type I integral membrane glycoproteins that exhibit homology in their cystine rich extracellular domains. Members of this family include TNF-RI, TNF-RII and CD40. Ligands for these receptors can be small, secreted proteins, such as TNF, or type II integral membrane proteins, as is the case for the CD40 ligand, CD40L. While the signal transduction mechanism of the TNF receptor superfamily is poorly understood, activation of TNF-R or CD40 have been shown to induce the nuclear translocation of NFkB. Members of the TRAF (TNF receptor-associated factor) family have been implicated in this process. Four members have thus far been described and are designated TRAF1, TRAF2, TRAF3 (variously referred to as CRAF1, LAP1 or CD40bp) and TRAF4. TRAF4, originally termed CART1, is specifically expressed in breast carcinomas, and is localized to the nucleus in such tissues.
TRUSTED_SUSTAINABILITY

Especificaciones

Antígeno TRAF4
Aplicaciones Immunohistochemistry (Paraffin), Western Blot
Clasificación Polyclonal
Concentración 500 μg/mL
Conjugado Unconjugated
Formulación PBS with 5mg BSA and 0.05mg sodium azide, 0.05mg thimerosal
génica TRAF4
N.º de referencia del gen Q61382, Q9BUZ4
Alias de gen A530032M13Rik; Cart1; cysteine-rich domain associated with ring and TRAF domain; cysteine-rich domain associated with RING and Traf domains protein 1; Cysteine-rich motif associated to RING and Traf domains protein 1; malignant 62; metastatic lymph node gene 62 protein; MLN 62; MLN62; msp2; RING finger protein 83; RNF83; RNF83malignant 62; TNF receptor associated factor 4; TNF receptor-associated factor 4; tnf receptor-associated factor 4b; traf4; TRAF4 protein; TRAF4 variant 6; traf4b; tumor necrosis receptor-associated factor 4A
Símbolos de los genes TRAF4
Especie del huésped Rabbit
Inmunógeno A synthetic peptide corresponding to a sequence at the C-terminus of human TRAF4 (437-454aa PKFISHQDIRKRNYVRDD).
Método de purificación Affinity chromatography
Cantidad 100 μg
Estado normativo RUO
Primario o secundario Primary
ID de gen (Entrez) 22032, 303285, 9618
Especies diana Human, Mouse, Rat
Contenido y almacenamiento -20°C
Tipo de producto Antibody
Formulario Lyophilized
Isotype IgG
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