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TOP2B Rabbit anti-Human, Mouse, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
140.00€ - 399.00€
Especificaciones
| Antígeno | TOP2B |
|---|---|
| Concentración | 0.39 mg/mL |
| Aplicaciones | Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot |
| Clasificación | Polyclonal |
| Conjugado | Unconjugated |
| Código de producto | Marca | Cantidad | Precio | Cantidad y disponibilidad | |||||
|---|---|---|---|---|---|---|---|---|---|
| Código de producto | Marca | Cantidad | Precio | Cantidad y disponibilidad | |||||
|
16830105
|
Proteintech
20549-1-AP-20UL |
20 μL |
140.00€
20 microlitros |
Fecha estimada de envío: 08-05-2024 Inicie sesión para ver el stock |
Por favor, inicie sesión para comprar este producto. ¿No tiene usuario web? Regístrese hoy mismo. | ||||
|
16820105
|
Proteintech
20549-1-AP-150UL |
150 μL |
399.00€
150 microlitros |
Fecha estimada de envío: 08-05-2024 Inicie sesión para ver el stock |
Por favor, inicie sesión para comprar este producto. ¿No tiene usuario web? Regístrese hoy mismo. | ||||
Descripción
The antibody is specific to TOP2B.
FOXO4 (Forkhead box O4) is encoded by the FOXO4 gene located on the X chromosome. It is also known as AFX1 or MLLT7 (Myeloid/Lymphoid or Mixed-Lineage Leukemia (Trithorax Homolog, Translocated To, 7) and is a member of the O class of forkhead/ winged helix family of transcription factors along with FOXO1, FOXO3 and FOXO6. FOXO4 is abundantly expressed in skeletal muscle and adipose tissue. FOXO4 binds to the Insulin Responsive Element (IRE) and activates downstream targets of Insulin/IGF1 signaling such as IGFBP1. However, the activation of another downstream target of the Insulin/IGF1 pathway, Akt, leads to phosphorylation of FOXO4 on specific Ser/Thr residues. This phosphorylation mediates binding of FOXO4 to 14-3-3 and eventual exit of FOXO4 from the nucleus.Especificaciones
| TOP2B | |
| Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot | |
| Unconjugated | |
| Rabbit | |
| Human, Mouse | |
| Q02880, Q64511 | |
| 21974, 7155 | |
| Peptide | |
| Primary | |
| -20°C | |
| TOP2B |
| 0.39 mg/mL | |
| Polyclonal | |
| Liquid | |
| RUO | |
| PBS with 50% glycerol and 0.02% sodium azide; pH 7.3 | |
| DNA topoisomerase 2 beta, TOP2B, top2beta, TOPIIB | |
| TOP2B | |
| IgG | |
| Antigen Affinity Chromatography | |
| Antibody |