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Invitrogen™ Tocilizumab Recombinant Monoclonal Antibody
Recombinant Monoclonal Antibody
Marca: Invitrogen™ MA558343
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Descripción
For reconstitution, add sterile, distilled water to achieve a final antibody concentration of 1 mg/mL. Gently shake to solubilize the protein completely. Do not vortex. Reconstituted products should be stored at -80 °.
Tocilizumab (Actemra) is a humanized monoclonal antibody that is developed by Hoffmann-La Roche and Chugai for the treatment of patients with rheumatoid arthritis (RA) and systemic juvenile idiopathic arthritis, a severe form of arthritis in children. Tocilizumab binds to the interleukin-6 receptor (IL-6R) and blocks its interaction with interleukin 6 (IL-6), hindering IL-6 from exerting its pro-inflammatory effects.
Especificaciones
| Tocilizumab Humanized | |
| Recombinant Monoclonal | |
| Unconjugated | |
| Actemra; Atlizumab; MRA; R-1569; RHPM-1; RO-4877533 | |
| Protein A | |
| RUO | |
| Human | |
| Antibody | |
| IgG1 κ |
| ELISA, Flow Cytometry, Functional Assay, Surface Plasmon Resonance | |
| 1 mg/mL | |
| 25mM histidine with 8% sucrose, 0.01% Tween 80 and no preservative; pH 6.2 | |
| Human | |
| 100 μg | |
| Primary | |
| -20°C, Avoid Freeze/Thaw Cycles | |
| Lyophilized |
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