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TNFRSF13C Mouse anti-Human, Clone:5A9B6, Abnova™
Mouse monoclonal antibody raised against partial recombinant human TNFRSF13C.
Marca: Abnova MAB17996.100ug
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Descripción
B cell-activating factor (BAFF) enhances B-cell survival in vitro and is a regulator of the peripheral B-cell population. Overexpression of Baff in mice results in mature B-cell hyperplasia and symptoms of systemic lupus erythematosus (SLE). Also, some SLE patients have increased levels of BAFF in serum. Therefore, it has been proposed that abnormally high levels of BAFF may contribute to the pathogenesis of autoimmune diseases by enhancing the survival of autoreactive B cells. The protein encoded by this gene is a receptor for BAFF and is a type III transmembrane protein containing a single extracellular cysteine-rich domain. It is thought that this receptor is the principal receptor required for BAFF-mediated mature B-cell survival. [provided by RefSeq]Especificaciones
| TNFRSF13C | |
| Monoclonal | |
| Unconjugated | |
| ELISA (1:10000) Flow Cytometry (1:200-1:400) Western Blot (1:100-1:500) The optimal working dilution should be determined by the end user. |
|
| TNFRSF13C | |
| Mouse | |
| 100 μg | |
| Human | |
| Antibody | |
| IgG2b |
| ELISA, Flow Cytometry, Western Blot | |
| 5A9B6 | |
| tumor necrosis factor receptor superfamily, member 13C | |
| In PBS (0.05% sodium azide) | |
| BAFF-R, BAFFR, CD268, MGC138235 | |
| Recombinant protein corresponding to amino acids 1-78 of human TNFRSF13C. | |
| 115650 | |
| Store at 4°C. For long term storage store at -20°C. Aliquot to avoid repeated freezing and thawing. |
|
| Liquid |
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