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Invitrogen™ TIM-4 Monoclonal Antibody (2A1H5)

Descripción
TIM-4 Monoclonal Antibody for Western Blot, ICC/IF, Flow, ELISA
The T cell immunoglobulin and mucin domain containing protein (TIM) family encodes cell surface receptors that are involved in the regulation of T helper (Th) -1 and -2 cell-mediated immunity. TIM-4, which is preferentially expressed on macrophages and dendritic cells, is the natural ligand of TIM-1, and this binding leads to T-cell expansion and cytokine production. Unlike other members of the TIM family, TIM-4 lacks a putative tyrosine phosphorylation signal sequence in its intracellular domain. The TIM-4 gene maps to a locus associated with predisposition to asthma in both mice and humans and with its connection to TIM-1-triggered Th2 responsiveness, may be considered as a candidate disease/predisposition gene for asthma.
Especificaciones
Especificaciones
| Antígeno | TIM-4 |
| Aplicaciones | ELISA, Flow Cytometry, Western Blot, Immunocytochemistry |
| Clasificación | Monoclonal |
| Clon | 2A1H5 |
| Concentración | 1 mg/mL |
| Conjugado | Unconjugated |
| Formulación | PBS with 0.05% sodium azide |
| génica | TIMD4 |
| N.º de referencia del gen | Q96H15 |
| Alias de gen | B430010N18Rik; RGD1564516; smuckler; soluble TIM 4; Spleen, mucin-containing, knockout of lymphotoxin protein; sTIM 4; T cell immunoglobulin and mucin domain containing 4; T-cell immunoglobulin and mucin domain containing 4; T-cell immunoglobulin and mucin domain-containing protein 4; T-cell immunoglobulin mucin receptor 4; T-cell membrane protein 4; Tim4; TIM-4; TIMD4; TIMD-4 |
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Título del producto
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