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Invitrogen™ Thyroglobulin Monoclonal Antibody (TG60), Invitrogen™
Mouse Monoclonal Antibody
Marca: Invitrogen™ MA110593
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Descripción
MA1-10593 detects Thyroglobulin, specifically both T3 and T4, from human samples. MA1-10593 has been successfully used in ELISA applications. The MA1-10593 immunogen is purified human Thyroglobulin.
The human thyroglobulin (hTg) is a high molecular weight glycoprotein (605 kDa) found in the thyroid follicular cells. It plays a central role in the uptake, incorporation, and regulated biosynthesis of thyroid hormones, T4 and T3. Thyroid disorders are, in large part, due to autoimmune origin, and anti-thyroglobulin autoantibodies were the first factor to be discovered. Anti-hTG is found in all thyroid autoimmune diseases (Hashimoto thyroiditis, Graves diseases), with the highest level observed in Hashimoto thyroiditis. Anti-hTG is also characteristic of thyroid cancer, and its determination can be used for the follow up of cancer patients.
Especificaciones
| Thyroglobulin | |
| Monoclonal | |
| 2.0 mg/mL | |
| PBS with no preservative; pH 7.4 | |
| P01266 | |
| TG | |
| Purified human Thyroglobulin. | |
| 500 μg | |
| Primary | |
| Human | |
| Antibody | |
| IgG1 |
| ELISA | |
| TG60 | |
| Unconjugated | |
| TG | |
| AITD3; cog; Colloid; congenital goiter; hereditary goitre; TG; Tgn; thyroglobulin; thyroglobulin precursor | |
| Mouse | |
| Protein A | |
| RUO | |
| 7038 | |
| -20°C, Avoid Freeze/Thaw Cycles | |
| Liquid |
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