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Thyroglobulin Antibody (2H11), Alexa Fluor™ 647, Novus Biologicals™

Mouse Monoclonal Antibody

Marca:  Novus Biologicals NBP2-33070AF647

Código de producto. 18175004

  • ONLINE EXCLUSIVE PRICE
    588.00€
    555.45€ / 0.10 ml
    Ahorro 32.55€
    5% Descuento

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Descripción

Descripción

Thyroglobulin Monoclonal specifically detects Thyroglobulin in Human, Mouse, Rat samples. It is validated for Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Paraffin.
TRUSTED_SUSTAINABILITY
Especificaciones

Especificaciones

Thyroglobulin
Monoclonal
Alexa Fluor 647
AITD3TGN, TDH3, Tg, thyroglobulin
Mouse
Protein A or G purified
RUO
Primary
monoclonal antibody 2H11 reacts with a partially defined epitope of human thyroglobulin. This epitope is different form the epitope recognized by monoclonal antibody 6E1. Thyroglobulin is a 660kDa dimeric pre-protein with multiple glycosylation sites. It is produced by and processed within the thyroid gland to produce the hormone thyroxine and triiodothyronine. Prior to forming dimers, thyroglobulin monomers undergo conformational maturation in the endoplasmic reticulation. The vast majority of follicular carcinomas of the thyroid will give positive immunoreactivity for anti-thyroglobulin even though sometimes only focally. Poorly differentiated carcinomas of the thyroid are frequently anti-thyroglobulin negative. Adenocarcinomas of other-than-thyroid origin do not react with this antibody. This antibody is useful in identification of thyroid carcinoma of the papillary and follicular types. Presence of thyroglobulin in metastatic lesions establishes the thyroid origin of tumor. Anti-thyroglobulin, combined with anti-calcitonin, can identify medullary carcinomas of the thyroid. Furthermore, anti-thyroglobulin, combined with anti-TTF1, can be a reliable marker to differentiate between primary thyroid and lung neoplasms.
Store at 4C in the dark.
IgG1 κ
Western Blot, Flow Cytometry, Immunohistochemistry (Paraffin)
2H11
Western Blot, Flow Cytometry, Immunohistochemistry-Paraffin
TG
Human thyroid follicular cells were used as immunogen to generate the antibody.
0.1 mL
Cancer, Cell Biology
7038
Human, Mouse, Rat
Purified
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