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Invitrogen™ TGFBR1 Monoclonal Antibody (234R32)
Mouse Monoclonal Antibody
Marca: Invitrogen™ AHO1552
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Descripción
TGFBR1 Monoclonal Antibody for Western Blot
TGFBR1 is a transmembrane serine/threonine kinase in the TGFBR1 superfamily, which also includes ACVRs and BMPRs. Upon binding TGF-b, TGFBR2 dimerizes with and activates TGFBR1 via phosphorylation leading to downstream phosphorylation of SMADs by TGFBR1. TGFBR1 forms a heteromeric complex with type II TGF-beta receptors when bound to TGF-beta, transducing the TGF-beta signal from the cell surface to the cytoplasm. The encoded protein is a serine/threonine protein kinase. Mutations in this gene have been associated with Loeys-Dietz aortic aneurysm syndrome (LDAS).
Especificaciones
| TGFBR1 | |
| Monoclonal | |
| 0.5 mg/mL | |
| PBS with 0.1% sodium azide; pH 7.4 | |
| P36897, P80204 | |
| TGFBR1 | |
| Recombinant human TGF-b R1 extracellular fragment. | |
| 100 μg | |
| Primary | |
| Human, Rat | |
| Antibody | |
| IgG1 κ |
| Western Blot | |
| 234R32 | |
| Unconjugated | |
| TGFBR1 | |
| AAT5; activin A receptor type II-like kinase, 53kDa; activin A receptor type II-like protein kinase of 53kD; Activin receptor-like kinase 5; ACVRLK4; ALK5; Alk-5; AU017191; ESK2; ESS1; LDS1; LDS1A; LDS2A; MSSE; mutant transforming growth factor beta receptor I; ser; serine/threonine-protein kinase receptor R4; SKR4; TbetaRI; tbetaR-I; tgf beta receptor 1; TGF-beta receptor type I; TGF-beta receptor type-1; TGF-beta type I receptor; TGFBR1; TGFR1; TGFR-1; Transfor; transforming growth factor beta receptor 1; transforming growth factor beta receptor I; transforming growth factor, beta receptor 1; transforming growth factor, beta receptor I; transforming growth factor, beta receptor I (activin A receptor type II-like kinase, 53kDa); transforming growth factor-beta receptor type I | |
| Mouse | |
| Affinity chromatography | |
| RUO | |
| 29591, 7046 | |
| -20°C | |
| Liquid |
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