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TGF alpha Monoclonal Antibody (MF9), Invitrogen™
Mouse Monoclonal Antibody
Marca: Invitrogen MA513907
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Descripción
MA5-13907 targets Transforming Growth Factor alpha in WB applications and shows reactivity with Bovine, Human, mouse, and Rat samples. The MA5-13907 immunogen is a 17-amino acid synthetic peptide from the carboxyl-terminus of Rat TGFalpha.
TGF-alpha is an EGF-related polypeptide growth factor that signals through the EGF receptor, and stimulates the proliferation of a wide range of epidermal and epithelial cells. It is produced by monocytes, keratinocytes, and various tumor cells. TGF-alpha induces anchorage-independence transformation in cultured cells. Human, murine and rat TGF-alpha are cross-species reactive. TGFalpha (aa 50) is a growth factor with 33% homology to EGF, binds to EGFR, activates tyrosine phosphorylation of the receptor, and stimulates cell proliferation. It plays a role in tumor initiation by inducing the reversible transformed phenotype.
Especificaciones
| TGF alpha | |
| Monoclonal | |
| 0.2 mg/mL | |
| PBS with 0.2% BSA and 0.09% sodium azide; pH 7.4 | |
| P01134, P01135, P48030 | |
| TGFA | |
| A 17-amino acid synthetic peptide from the carboxyl-terminus of Rat TGFalpha | |
| 500 μL | |
| Primary | |
| Bovine, Human, Mouse, Rat | |
| Antibody | |
| IgG1 κ |
| Western Blot | |
| MF9 | |
| Unconjugated | |
| TGFA | |
| EGF-like TGF; ETGF; I79_019067; LOC100009150; Protransforming growth factor alpha; RATTGFAA; TFGA; TGF a; TGF type 1; TGF a; TGFA; TGFAA; TGFalpha; TGF-alpha; TGFa; Transforming growth factor; Transforming growth factor alpha; transforming growth factor, alpha; transforming growth factor-alpha; wa1; wa-1; waved 1 | |
| Mouse | |
| Protein G | |
| RUO | |
| 21802, 24827, 540388, 7039 | |
| 4° C | |
| Liquid |
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