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TGF alpha Monoclonal Antibody (MF9), Invitrogen™
Descripción
MA5-13907 targets Transforming Growth Factor alpha in WB applications and shows reactivity with Bovine, Human, mouse, and Rat samples. The MA5-13907 immunogen is a 17-amino acid synthetic peptide from the carboxyl-terminus of Rat TGFalpha.
TGF-alpha is an EGF-related polypeptide growth factor that signals through the EGF receptor, and stimulates the proliferation of a wide range of epidermal and epithelial cells. It is produced by monocytes, keratinocytes, and various tumor cells. TGF-alpha induces anchorage-independence transformation in cultured cells. Human, murine and rat TGF-alpha are cross-species reactive. TGFalpha (aa 50) is a growth factor with 33% homology to EGF, binds to EGFR, activates tyrosine phosphorylation of the receptor, and stimulates cell proliferation. It plays a role in tumor initiation by inducing the reversible transformed phenotype.
Especificaciones
Especificaciones
| Antígeno | TGF alpha |
| Aplicaciones | Western Blot |
| Clasificación | Monoclonal |
| Clon | MF9 |
| Concentración | 0.2 mg/mL |
| Conjugado | Unconjugated |
| Formulación | PBS with 0.2% BSA and 0.09% sodium azide; pH 7.4 |
| génica | TGFA |
| N.º de referencia del gen | P01134, P01135, P48030 |
| Alias de gen | EGF-like TGF; ETGF; I79_019067; LOC100009150; Protransforming growth factor alpha; RATTGFAA; TFGA; TGF a; TGF type 1; TGF a; TGFA; TGFAA; TGFalpha; TGF-alpha; TGFa; Transforming growth factor; Transforming growth factor alpha; transforming growth factor, alpha; transforming growth factor-alpha; wa1; wa-1; waved 1 |
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Título del producto
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