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TEK Polyclonal Antibody, Invitrogen™
Descripción
Immunogen sequence: VISWTILDGY SISSITIRYK VQGKNEDQHV DVKIKNATIT QYQLKGLEPE TAYQVDIFAE NNIGSSNPAF SHELVTLPES QAPADL
TIE2, also known as TEK tyrosine kinase, TIE2 gene is mapped to 9p21.2. This gene encodes a receptor that belongs to the protein tyrosine kinase Tie2 family. The encoded protein possesses a unique extracellular region that contains two immunoglobulin-like domains, three epidermal growth factor (EGF)-like domains and three fibronectin type III repeats. The ligand angiopoietin-1 binds to this receptor and mediates a signaling pathway that functions in embryonic vascular development. Immunoblotting showed that TIE2 expression was increased by thyroid-stimulating hormone and agents that increased intracellular cAMP. HSCs expressing the receptor tyrosine kinase TIE2 are quiescent and antiapoptotic and comprise a side population of HSCs that adhere to osteoblasts in the bone marrow niche.
Especificaciones
Especificaciones
| Antígeno | TEK |
| Aplicaciones | Immunocytochemistry, Immunofluorescence |
| Clasificación | Polyclonal |
| Conjugado | Unconjugated |
| Formulación | PBS with 40% glycerol and 0.02% sodium azide; pH 7.2 |
| génica | TEK |
| N.º de referencia del gen | Q02763 |
| Alias de gen | AA517024; Angiopoietin-1 receptor; CD202b; CD202b antigen; EC 2.7.10; EC 2.7.10.1; Endothelial tyrosine kinase; hTIE2; Hyk; mTIE2; p140 TEK; STK1; Tek; TEKT1; Tektin-1; Tie2; Tie-2; Tunica interna endothelial cell kinase; Tyrosine kinase with Ig and EGF homology domains-2; Tyrosine-protein kinase receptor TEK; Tyrosine-protein kinase receptor Tie-2; VMCM; VMCM1 |
| Símbolos de los genes | TEK |
| Especie del huésped | Rabbit |
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Título del producto
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