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TAAR1 Polyclonal Antibody, Invitrogen™
Rabbit Polyclonal Antibody
Marca: Invitrogen PA577759
Detalles adicionales : Peso : 0.01000kg
Descripción
Product is shipped at room temperature as a lyophilized powder and should be stored at -20 °C upon receipt. Reconstitution: add 50 μL of deionized water.
TA1 has been reported in human brain, dorsal root ganglion, olfactory bulb, kidney, liver, lung, pancreas, prostate, skeletal muscle, small intestine, spleen, spinal cord, and stomach. An EST for TA1 has been identified from a human stomach cancer library. G-protein Coupled Receptors (GPCRs) comprise one of the largest families of signaling molecules with more thana thousandmembers currently predicted to exist. All GPCRs share a structural motif consisting of seven membrane-spanning helices, and exist in both active and inactive forms. An array of activating ligands participate in the conformation of GPCRs which leads to signaling via G-proteins and downstream effectors. Ongoing studies have also shown the vast series of reactions which participate in the negative regulation of GPCRs. This turn-off activity has tremendous implications for the physiological action of the cell, and continues to drive pharmacological research for new drug candidates.Especificaciones
TAAR1 | |
Polyclonal | |
Unconjugated | |
TAAR1 | |
TA1, Trace amine-associated receptor 1, TAAR1 | |
Rabbit | |
Antigen affinity chromatography | |
RUO | |
111174, 113914, 134864 | |
-20°C | |
Lyophilized |
Western Blot | |
0.85 mg/mL | |
PBS with 1% BSA and 0.05% sodium azide; pH 7.4 | |
Q923Y8, Q923Y9, Q96RJ0 | |
TAAR1 | |
Peptide (C)KMVLFGKIFQKDS, corresponding to amino acid residues 313-325 of rat Trace amine receptor 1 | |
50 μL | |
Primary | |
Human, Mouse, Rat | |
Antibody | |
IgG |