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SV40 Large T-Antigen Monoclonal Antibody (PAb101 (412)), Invitrogen™
Descripción
This antibody reacts with native and denatured large T-antigen. It does not react with the small T-antigen of SV40 or the large T-antigen of BKV, human papovavirus.
The SV40 T antigen is encoded by the early region of the SV40 genome. The large T antigen binds DNA, and complexes with a 53,000 dalton cellular protein, p53, which is required for initiation of viral DNA replication during lytic growth. In addition, the large T antigen binds DNA polymerase and the transcription factor AP-2 and forms a specific complex with the P105 product of the retinoblastoma susceptibility gene.
Especificaciones
Especificaciones
| Antígeno | SV40 Large T-Antigen |
| Aplicaciones | Immunocytochemistry, Immunoprecipitation, Western Blot |
| Clasificación | Monoclonal |
| Clon | PAb101 (412) |
| Concentración | 0.2 mg/mL |
| Conjugado | Unconjugated |
| Formulación | PBS with 0.2% BSA and 0.09% sodium azide; pH 7.4 |
| Alias de gen | simian vacuolating virus 40; simian virus; Simian virus 40; sv40 large t antigen; sv40 virus large t antigen |
| Especie del huésped | Mouse |
| Inmunógeno | SV40 transformed mouse line B4 |
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Título del producto
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