missing translation for 'onlineSavingsMsg'
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Descripción
The MW of STIM1 is about 80-90 kDa which may be due to the phosphorylation or glycosylation forms. 11565-1-AP is rabbit polyclonal antibody raised against the N-terminal of human STIM1.
This gene encodes a type 1 transmembrane protein that mediates Ca2+ influx after depletion of intracellular Ca2+ stores by gating of store-operated Ca2+ influx channels (SOCs). It is one of several genes located in the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocrotical carcinoma, and lung, ovarian, and breast cancer. This gene may play a role in maligcies and disease that involve this region, as well as early hematopoiesis, by mediating attachment to stromal cells. This gene is oriented in a head-to-tail configuration with the ribonucleotide reductase 1 gene (RRM1), with the 3′ end of this gene situated 1.6 kb from the 5′ end of the RRM1 gene.
Especificaciones
Especificaciones
| Antígeno | STIM1 |
| Aplicaciones | Immunofluorescence, Flow Cytometry, Immunohistochemistry (Paraffin), Immunoprecipitation, Immunocytochemistry |
| Clasificación | Polyclonal |
| Concentración | 0.42 mg/mL |
| Conjugado | Unconjugated |
| Formulación | PBS with 50% glycerol and 0.1% sodium azide; pH 7.3 |
| génica | STIM1 |
| N.º de referencia del gen | P70302, Q13586 |
| Alias de gen | D11S4896E, GOK, STIM1, stromal interaction molecule 1 |
| Símbolos de los genes | STIM1 |
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Título del producto
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