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SR Monoclonal Antibody (16H3 (16H3E8)), Invitrogen™
Mouse Monoclonal Antibody
Marca: Invitrogen 339300
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Descripción
This monoclonal antibody can be used to detect a sub-set of the non-snRNP splicing factors termed SR proteins. The antibody detects SRp75, SRp55, SRp40, and SRp20 but not SRp30a or b (ASF/SF2, SC-35) proteins. 16H3 also recognizes approximately 20 distinct nuclear proteins including the U1 70K component of the U1 snRNP and both subunits of U2AF. The epitope detected by the 16H3 monoclonal antibody has been termed the alternating arginine domain and is composed almost exclusively of argnine alternating with glutamate and aspartate. 16H3 targets are predominantly nuclear, nonnucleolar, and are localized to active sites of polymerase II transcription.
SR Monoclonal antibody specifically detects SR in Bovine, Canine, Chicken, Drosophila, Human, Mouse, Rabbit, Rat, Xenopus laevis samples. It is validated for ELISA, Immunocytochemistry, Western Blot.
Especificaciones
| SR | |
| Monoclonal | |
| 0.5 mg/mL | |
| PBS with 0.1% sodium azide; pH 7.4 | |
| G3V6S8, O18776, O35326, P84103, P84104, Q08170, Q09167, Q13243, Q13247, Q3B7L6, Q3SZR8, Q3TWW8, Q8VE97 | |
| SRSF3, SRSF4, SRSF5, SRSF6 | |
| Purified, de-phosphorylated bovine Srp55 and Drosophila p55-GST. The 16H3 epitope has been mapped to a 40-amino acid polypeptide composed almost exclusively of arginine alternating with glutamate and aspartate | |
| 100 μg | |
| Primary | |
| Bovine, Canine, Chicken, Drosophila, Human, Mouse, Rabbit, Rat, X. laevis | |
| Antibody | |
| IgG1 κ |
| ELISA, Immunocytochemistry, Western Blot | |
| 16H3 (16H3E8) | |
| Unconjugated | |
| SRSF3 | |
| 1210001E11Rik; 5730499P16Rik; AI314910; AL024116; AW146126; AW550192; B52; Cl-4; Delayed-early protein HRS; epididymis secretory protein Li 91; HEL-S-91; HRS; hypothetical protein; insulin-induced growth response protein CL-4; LOW QUALITY PROTEIN: serine/arginine-rich splicing factor 4; MNCb-2616; pre-mRNA splicing factor SRp20; pre-mRNA-splicing factor SRP20; Pre-mRNA-splicing factor SRP40; pre-mRNA-splicing factor SRP55; Pre-mRNA-splicing factor SRP75; Protein X16; RGD1561347; serine and arginine rich splicing factor 3; serine and arginine rich splicing factor 4; serine and arginine rich splicing factor 5; serine and arginine rich splicing factor 6; serine/arginine-rich splicing factor 3; Serine/arginine-rich splicing factor 4; serine/arginine-rich splicing factor 5; Serine/arginine-rich splicing factor 6; SFRS3; Sfrs4; Sfrs5; Sfrs6; splicing factor; splicing factor arginine/serine-rich 5 (SRp40 HRS); splicing factor SRp55; splicing factor SRp55 homolog; splicing factor SRp55-1; spli | |
| Mouse | |
| Protein A | |
| RUO | |
| 100008654, 100340192, 100347748, 100350179, 20383, 20384, 29667, 361814, 362264, 362612, 403667, 403687, 419116, 419600, 419815, 423258, 478160, 490754, 507828, 510474, 540276, 57317, 614310, 6428, 6429, 6430, 6431, 67996 | |
| Maintain refrigerated at 2-8°C for up to 1 month. For long term storage store at -20°C | |
| Liquid |