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Invitrogen™ Spectrin beta-4 Polyclonal Antibody, Invitrogen™
Descripción
Spectrin is the major constituent of the cytoskeletal network underlying the erthrocyte plasma membrane and determines cell shape, arrangement of transmembrane proteins and organization of organelles. It is expressed at very low levels in many tissues, with the strongest expression in the cerebellum, spinal cord, stomach, pituitary gland, liver, pancreas, salivary gland, kidney, bladder and heart. Spectrin beta 4 is a non-erythrocyte member, and is expressed in the brain and pancreatic islets and localisted to the nuclear matrix, cytoplasmic vesicles and PML nuclear bodies. Beta4 spectrins are also essential for membrane stability and the molecular organization of the nodes of Ranvier.
Especificaciones
Especificaciones
| Antígeno | Spectrin beta-4 |
| Aplicaciones | Immunohistochemistry (Paraffin), Western Blot |
| Clasificación | Polyclonal |
| Concentración | 0.5 mg/mL |
| Conjugado | Unconjugated |
| Formulación | PBS with 50% glycerol and 0.05% ProClin 300; pH 7.4 |
| génica | SPTBN4 |
| N.º de referencia del gen | Q9H254 |
| Alias de gen | 1700022P15Rik; 5830426A08Rik; beta-IV spectrin; beta-spectrin 4; dyn; EMBL BAB83243.1; KIAA1642; lnd; lumbosacral neuroaxonal dystrophy; neuroaxonal dystrophy; nmf261; nmf379; quivering; qv; ROSA62; SpbIV; spectrin beta 4; spectrin beta chain, brain 3; spectrin beta chain, non-erythrocytic 4; spectrin beta, non-erythrocytic 4; spectrin, beta, non-erythrocytic 4; spectrin, non-erythroid beta chain 3; SPNB4; SPTBN3; SPTBN4 |
| Símbolos de los genes | SPTBN4 |
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