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Invitrogen™ SP1 Recombinant Rabbit Monoclonal Antibody (5I3A8)
Rabbit Recombinant Monoclonal Antibody
Marca: Invitrogen™ MA535331
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Descripción
Immunogen sequence: TTLTPIASAA SIPAGTVTVN AAQLSSMPGL QTINLSALGT SGIQVHPIQG LPLAIANAPG DHGAQLGLHG AGGDGIHDDT AGGEEGENSP DAQPQAGRRT R.
SP1 is a transcription factor that can activate or repress transcription in response to physiological and pathological stimuli. Binds with high affinity to GC-rich motifs and regulates the expression of a large number of genes involved in a variety of processes such as cell growth, apoptosis, differentiation and immune responses. Highly regulated by post-translational modifications (phosphorylations, sumoylation, proteolytic cleavage, glycosylation and acetylation). Binds also the PDGFR-alpha G-box promoter. May have a role in modulating the cellular response to DNA damage. Implicated in chromatin remodeling. Plays a role in the recruitment of SMARCA4/BRG1 on the c-FOS promoter. Plays an essential role in the regulation of FE65 gene expression.
Especificaciones
| SP1 | |
| Recombinant Monoclonal | |
| 1.5 mg/mL | |
| PBS with 50% glycerol, 0.05% BSA and 0.02% sodium azide; pH 7.3 | |
| O89090, P08047, Q01714 | |
| SP1 | |
| Synthetic peptide. | |
| 100 μL | |
| Primary | |
| Human, Mouse, Rat | |
| Antibody | |
| IgG |
| ChIP Assay, ChIP sequencing (ChIP-seq), ELISA, Immunohistochemistry (Paraffin), Western Blot, CUT&RUN, Immunocytochemistry | |
| 5I3A8 | |
| Unconjugated | |
| SP1 | |
| 1110003E12Rik; AA450830; AI845540; HGNC:11205; SP1; Sp1 transcription factor; Sp1-1; specificity protein 1; trans-acting transcription factor 1; transcription factor Sp1; TSFP1 | |
| Rabbit | |
| Affinity Chromatography | |
| RUO | |
| 20683, 24790, 6667 | |
| -20°C, Avoid Freeze/Thaw Cycles | |
| Liquid |
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