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Invitrogen™ SP1 Recombinant Rabbit Monoclonal Antibody (5I3A8)

Descripción
SP1 Recombinant Monoclonal Antibody for ChIP, ChIP-seq, CUT&RUN, ELISA, ICC/IF, IHC (P), Western Blot
SP1 is a transcription factor that can activate or repress transcription in response to physiological and pathological stimuli. Binds with high affinity to GC-rich motifs and regulates the expression of a large number of genes involved in a variety of processes such as cell growth, apoptosis, differentiation and immune responses. Highly regulated by post-translational modifications (phosphorylations, sumoylation, proteolytic cleavage, glycosylation and acetylation). Binds also the PDGFR-alpha G-box promoter. May have a role in modulating the cellular response to DNA damage. Implicated in chromatin remodeling. Plays a role in the recruitment of SMARCA4/BRG1 on the c-FOS promoter. Plays an essential role in the regulation of FE65 gene expression.
Especificaciones
Especificaciones
| Antígeno | SP1 |
| Aplicaciones | ChIP Assay, ChIP sequencing (ChIP-seq), ELISA, Immunohistochemistry (Paraffin), Western Blot, CUT&RUN, Immunocytochemistry |
| Clasificación | Recombinant Monoclonal |
| Clon | 5I3A8 |
| Concentración | 1.5 mg/mL |
| Conjugado | Unconjugated |
| Formulación | PBS with 50% glycerol, 0.05% BSA and 0.02% sodium azide; pH 7.3 |
| génica | SP1 |
| N.º de referencia del gen | O89090, P08047, Q01714 |
| Alias de gen | 1110003E12Rik; AA450830; AI845540; HGNC:11205; SP1; Sp1 transcription factor; Sp1-1; specificity protein 1; trans-acting transcription factor 1; transcription factor Sp1; TSFP1 |
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Título del producto
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