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Invitrogen™ SMC1 Monoclonal Antibody (5E10)
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Código de producto. 16386334 Tienda Thermo Scientific Productos
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Cantidad:
100 μL
Tamaño de la unidad:
100 microlitros
Código de producto. Cantidad unitSize
16386334 100 μL 100 microlitros
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Código de producto. 16386334

Marca: Invitrogen™ MA532929

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Mouse Monoclonal Antibody

Purity is > 95% by SDS-PAGE.

Structural Maintenance of Chromosomes (SMC) family proteins play critical roles in various nuclear events that require structural changes of chromosomes, including mitotic chromosome organization, DNA recombination and repair and global transcriptional repression. The chromo proteins are conserved in eukaryotes and lead to mitotic chromosome segregatior defects. This suggests a critical function of SMC family proteins in mitotic chromosome dynamics. SMC1 and SMC3 form a heterodimeric complex required for metaphase progression in mitotic cells. Specifically this SMC1/SMC3 complex is responsible for sister chromatid cohesion during metaphase. Mutations in the gene can lead to Cornelia de Lange syndrome 2.
TRUSTED_SUSTAINABILITY

Especificaciones

Antígeno SMC1
Aplicaciones Western Blot
Clasificación Monoclonal
Clon 5E10
Concentración 1 mg/mL
Conjugado Unconjugated
Formulación PBS with 50% glycerol and 0.02% sodium azide; pH 7.2
génica SMC1A
N.º de referencia del gen Q14683, Q8NDV3
Alias de gen 14S cohesin SMC1 subunit; 5830426I24Rik; CDLS2; chromosome segregation protein SmcB; DKFZp686L19178; DXhXs423e; DXS423E; KIAA0178; MGC138332; mitosis-specific chromosome segregation protein like protein beta; mKIAA0178; RP6-29D12.1; Sb1.8; segregation of mitotic chromosomes 1; segregation of mitotic chromosomes b; segregation of mitotic chromosomes-like 1; SM1A; SMC; SMC (segregation of mitotic chromosomes 1)-like 1; SMC protein; SMC protein 1A; SMC protein 1B; SMC1; SMC1 (structural maintenance of chromosomes 1, yeast)-like 1; SMC1 protein; SMC1 protein cohesin subunit; SMC1 structural maintenance of chromosomes 1-like 1; SMC1 structural maintenance of chromosomes 1-like 2; Smc1a; SMC-1A; smc1a.L; smc1aa; Smc1alpha; SMC-1-alpha; SMC1alpha protein; Smc1b; SMC-1B; SMC1BETA; SMC-1-beta; SMC1L1; Smc1l2; Smcb; SMC-like 1; SMC-protein; structural maintenace of chromosomes 1B; structural maintenance of chromosomes 1; structural maintenance of chromosomes 1 like 1; structural maintenance of chromosomes 1A; structural maintenance of chromosomes 1A a; structural maintenance of chromosomes 1A L homeolog; structural maintenance of chromosomes 1B; structural maintenance of chromosomes protein 1A; Structural maintenance of chromosomes protein 1B; Unknown (protein for IMAGE:8058685); XELAEV_18000030mg; xsmc1
Símbolos de los genes SMC1A, SMC1B
Especie del huésped Mouse
Inmunógeno Synthetic peptide, corresponding to the C-terminus of Human SMC1A.
Método de purificación Antigen affinity chromatography
Cantidad 100 μL
Estado normativo RUO
Primario o secundario Primary
ID de gen (Entrez) 27127, 8243
Especies diana Human
Contenido y almacenamiento Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Tipo de producto Antibody
Formulario Liquid
Isotype IgG1
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