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  6. Invitrogen™ SETD7 Monoclonal Antibody (7C1B7E1), Invitrogen™

Invitrogen™ SETD7 Monoclonal Antibody (7C1B7E1), Invitrogen™

Código de producto. p-7240440
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Cantidad:
50 μL
100 μL
Tamaño de la unidad:
100 microlitros
50 microlitros
Código de producto. Cantidad unitSize
17789843 50 μL 50 microlitros
17729573 100 μL 100 microlitros
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Código de producto. 17789843

Marca: Invitrogen™ MA543500

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Descripción

Mouse Monoclonal Antibody

Specificity: Human SETD7/SET7/9

Histone methyltransferase that specifically monomethylates 'Lys-4' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. Plays a central role in the transcriptional activation of genes such as collagenase or insulin. Recruited by IPF1/PDX-1 to the insulin promoter, leading to activate transcription. Has also methyltransferase activity toward non-histone proteins such as p53/TP53, TAF10, and possibly TAF7 by recognizing and binding the [KR]-[STA]-K in substrate proteins. Monomethylates 'Lys-189' of TAF10, leading to increase the affinity of TAF10 for RNA polymerase II. Monomethylates 'Lys-372' of p53/TP53, stabilizing p53/TP53 and increasing p53/TP53-mediated transcriptional activation. [UniProt].
TRUSTED_SUSTAINABILITY

Specifications

Antígeno SETD7
Aplicaciones ELISA
Clasificación Monoclonal
Clon 7C1B7E1
Concentración 1 mg/mL
Conjugado Unconjugated
Formulación PBS with no preservative
génica Setd7
N.º de referencia del gen Q8WTS6
Alias de gen 1600028F23Rik; FLJ21193; H3-K4 methyltransferase; H3-K4-HMTase; H3-K4-HMTase SETD7; H3K4MT; Histone H3-K4 methyltransferase SETD7; histone H3-lysine 4-specific methyltransferase; histone-lysine N-methyltransferase SETD7; Kiaa1717; KMT7; lysine N-methyltransferase 7; mKIAA1717; OTTHUMP00000220049; SET domain containing (lysine methyltransferase) 7; SET domain containing 7, histone lysine methyltransferase; SET domain containing 7, lysine methyltransferase; SET domain containing lysine methyltransferase 7; SET domain-containing protein 7; Set7; Set7/9; SET9; Setd7
Símbolos de los genes Setd7
Especie del huésped Mouse
Inmunógeno Recombinant Human SETD7 protein.
Método de purificación Protein A
Cantidad 50 μL
Estado normativo RUO
Primario o secundario Primary
ID de gen (Entrez) 80854
Especies diana Human
Contenido y almacenamiento -20°C, Avoid Freeze/Thaw Cycles
Tipo de producto Antibody
Formulario Liquid
Isotype IgG2b
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