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SETD7 Monoclonal Antibody (7C1B7E1), Invitrogen™
Mouse Monoclonal Antibody
258.00€ - 449.00€
Especificaciones
Antígeno | SETD7 |
---|---|
Clon | 7C1B7E1 |
Concentración | 1 mg/mL |
Aplicaciones | ELISA |
Clasificación | Monoclonal |
Código de producto | Marca | Cantidad | Precio | Cantidad y disponibilidad | |||||
---|---|---|---|---|---|---|---|---|---|
Código de producto | Marca | Cantidad | Precio | Cantidad y disponibilidad | |||||
17789843
|
Invitrogen
MA543500 |
50 μL |
258.00€
50 microlitros |
Por favor, inicie sesión para comprar este producto. ¿No tiene usuario web? Regístrese hoy mismo. | |||||
17729573
|
Invitrogen
MA543017 |
100 μL |
449.00€
100 microlitros |
Por favor, inicie sesión para comprar este producto. ¿No tiene usuario web? Regístrese hoy mismo. | |||||
Descripción
Specificity: Human SETD7/SET7/9
Histone methyltransferase that specifically monomethylates 'Lys-4' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. Plays a central role in the transcriptional activation of genes such as collagenase or insulin. Recruited by IPF1/PDX-1 to the insulin promoter, leading to activate transcription. Has also methyltransferase activity toward non-histone proteins such as p53/TP53, TAF10, and possibly TAF7 by recognizing and binding the [KR]-[STA]-K in substrate proteins. Monomethylates 'Lys-189' of TAF10, leading to increase the affinity of TAF10 for RNA polymerase II. Monomethylates 'Lys-372' of p53/TP53, stabilizing p53/TP53 and increasing p53/TP53-mediated transcriptional activation. [UniProt]Especificaciones
SETD7 | |
1 mg/mL | |
Monoclonal | |
Liquid | |
RUO | |
PBS with no preservative | |
1600028F23Rik; FLJ21193; H3-K4 methyltransferase; H3-K4-HMTase; H3-K4-HMTase SETD7; H3K4MT; Histone H3-K4 methyltransferase SETD7; histone H3-lysine 4-specific methyltransferase; histone-lysine N-methyltransferase SETD7; Kiaa1717; KMT7; lysine N-methyltransferase 7; mKIAA1717; OTTHUMP00000220049; SET domain containing (lysine methyltransferase) 7; SET domain containing 7, histone lysine methyltransferase; SET domain containing 7, lysine methyltransferase; SET domain containing lysine methyltransferase 7; SET domain-containing protein 7; Set7; Set7/9; SET9; Setd7 | |
Setd7 | |
IgG2b | |
Protein A | |
Antibody |
7C1B7E1 | |
ELISA | |
Unconjugated | |
Mouse | |
Human | |
Q8WTS6 | |
80854 | |
Recombinant Human SETD7 protein. | |
Primary | |
-20° C, Avoid Freeze/Thaw Cycles | |
Setd7 |
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Título del producto
SETD7 Monoclonal Antibody (7C1B7E1), Invitrogen™