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Invitrogen™ SEPT2 Recombinant Rabbit Monoclonal Antibody (JB41-30)

Descripción
Positive Control: Mouse brain, K562, SHSY-5Y, HUVEC, HepG2, human colon cancer tissue, human kidney tissue, rat brain tissue.
Septin 2 is a filament-forming cytoskeletal GTPase. Septin 2 is required for normal organization of the actin cytoskeleton and plays a role in the biogenesis of polarized columnar-shaped epithelium by maintaining polyglutamylated microtubules, thus facilitating efficient vesicle transport, and by impeding MAP4 binding to tubulin. It is required for the progression through mitosis, and it forms a scaffold at the midplane of the mitotic splindle required to maintain CENPE localization at kinetochores and consequently chromosome congression. During anaphase, Septin 2 may be required for chromosome segregation and spindle elongation. Septin 2 also plays a role in ciliogenesis and collective cell movements.
Especificaciones
Especificaciones
| Antígeno | SEPT2 |
| Aplicaciones | Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry |
| Clasificación | Recombinant Monoclonal |
| Clon | JB41-30 |
| Concentración | 1 mg/mL |
| Conjugado | Unconjugated |
| Formulación | TBS with 40% glycerol, 0.05% BSA and 0.05% sodium azide; pH 7.4 |
| génica | SEPTIN2 |
| N.º de referencia del gen | Q15019 |
| Alias de gen | 2-Sep; AW208991; DIFF6; hNedd5; KIAA0158; mKIAA0158; NEDD5; Nedd-5; Neural precursor cell expressed developmentally down-regulated protein 5; neural precursor cell expressed, developmentally down-regulated 5; neural precursor cell expressed, developmentally down-regulated gene 5; Pnutl3; Sept2; septin 2; Septin2; septin-2; Vascular endothelial cell specific protein 11; Vesp11 |
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Título del producto
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