missing translation for 'onlineSavingsMsg'
Learn More
  1. Home
  2. Products
  3. Anticuerpos
  4. Anticuerpos primarios
  5. Todos los anticuerpos primarios
  6. PeproTech SCF Polyclonal Antibody, Biotin, PeproTech®, Invitrogen™

PeproTech SCF Polyclonal Antibody, Biotin, PeproTech®, Invitrogen™

Código de producto. 17843303
Change view
Click to view available options
Cantidad:
2 x 500 μg
25 μg
50 μg
500 μg
Tamaño de la unidad:
1 miligramo
25 microgramos
50 microgramos
500 microgramos
Código de producto. Cantidad unitSize
17843303 25 μg 25 microgramos
17823043 50 μg 50 microgramos
17803673 2 x 500 μg 1 miligramo
30054406 500 μg 500 microgramos
4 options
Este artículo no se puede devolver. Vea la política de devoluciones

Código de producto. 17843303

Marca: PeproTech 500P71BT25UG

Por favor, para comprar este producto. ¿No tiene usuario web? Regístrese hoy mismo.

Este artículo no se puede devolver. Vea la política de devoluciones

Descripción

Rabbit Polyclonal Antibody

AA Sequence of recombinant protein: MKEICGNPVT DNVKDITKLV ANLPNDYMIT LNYVAGMDVL PSHCWLRDMV IQLSLSLTTL LDKFSNISEG LSNYSIIDKL GKIVDDLVLC MEENAPKNIK ESPKRPETRS FTPEEFFSIF NRSIDAFKDF MVASDTSDCV LSSTLGPEKD SRVSVTKPFM LPPVA. Preparation: Produced from sera of rabbits immunized with highly pure Recombinant Murine SCF. Anti-Murine SCF-specific antibody was purified by affinity chromatography and then biotinylated. Sandwich ELISA: To detect mSCF by sandwich ELISA (using 100 μL/well antibody solution) a concentration of 0.25-1.0 μg/mL of this antibody is required. This biotinylated polyclonal antibody, in conjunction with PeproTech Polyclonal Anti-Murine SCF (500-P71) as a capture antibody, allows the detection of at least 0.2-0.4 ng/well of Recombinant mSCF. Western Blot: To detect mSCF by Western Blot analysis this antibody can be used at a concentration of 0.1-0.2 μg/mL. Used in conjunction with compatible secondary reagents the detection limit for Recombinant mSCF is 1.5-3.0 ng/lane, under either reducing or non-reducing conditions. 500-P71BT-1MG will be provided as 2 x 500 μg

Stem cell factor (SCF) is the ligand of the c-Kit oncogene and is expressed by various structural and inflammatory cells in the airways. Binding of SCF by the c-Kit receptor leads to homodimerization of the receptor and the activation of signalling pathways such as PI-3, PLC-gamma, Jak/STAT, and MAP kinase pathways. SCF expression leads to the induction of mast cell survival and the expression and release of histamine, pro-inflammatory cytokines and chemokines. The inhibition of the SCF/c-Kit pathway leads to a decrease in histamine levels, mast cell and eosinophil infiltration, IL-4 production and airway hyperresponsiveness, suggesting this pathway may be a useful therapeutic target in inflammatory diseases such as asthma. At least two isoforms of SCF are known to exist.
TRUSTED_SUSTAINABILITY

Especificaciones

Antígeno SCF
Aplicaciones ELISA, Western Blot
Clasificación Polyclonal
Concentración 0.1-1.0 mg/mL
Conjugado Biotin
Formulación PBS with no preservative
génica Kitl
N.º de referencia del gen P20826
Alias de gen 710-712; blz; c-Kit ligand; Clo; cloud gray; Con; contrasted; CSF; DCUA; DFNA69; DKFZp686F2250; familial progressive hyperpigmentation 2; FPH2; FPHH; Gb; grizzle-belly; hematopoietic growth factor KL; H-SCF; Kit ligand; Kitl; Kitlg; kit-ligand; KL-1; Mast cell growth factor; MGF; M-SCF; Processed kit ligand; SCF; SF; SHEP7; sKITLG; Sl; SLF; Soluble KIT ligand; Steel factor; steel factor/kit ligand; stem cell factor; stem cell factor KL-1; stem cell factor, CSF
Símbolos de los genes Kitl
Especie del huésped Rabbit
Inmunógeno E.coli-derived, 18.3 kDa Recombinant Murine SCF.
Método de purificación Antigen affinity chromatography
Cantidad 25 μg
Estado normativo RUO
Primario o secundario Primary
ID de gen (Entrez) 17311
Especies diana Mouse
Contenido y almacenamiento -20°C
Tipo de producto Antibody
Formulario Lyophilized
Mostrar más Mostrar menos
Product Title
Select an issue

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.