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  6. Invitrogen™ RT1.D Monoclonal Antibody (OX-17), FITC

Invitrogen™ RT1.D Monoclonal Antibody (OX-17), FITC

Código de producto. 15368340
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Cantidad:
100 μg
500 μg
Tamaño de la unidad:
100 microgramos
500 microgramos
Código de producto. Cantidad unitSize
15368340 500 μg 500 microgramos
15358340 100 μg 100 microgramos
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Código de producto. 15368340

Marca: Invitrogen™ MA517438

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Descripción

Mouse Monoclonal Antibody

anti-rat RT1.D monoclonal antibody recognizes a monomorphic determinant on the α chain of the rat Ia antigen and appears to be the rat homologue of mouse Ia-E. It recognizes the rat Ia product present on B, but not T cells from lymph node or thoracic duct lymph. It does not bind to thymocytes or erythrocytes. The antibody does not cross-react with rat Ia-A or mouse Ia-E antigen, but rabbit antibody raised against the antibody affinity column-purified MRC OX-17 antigen cross-reacted on tissues of mice expressing Ia-E mouse antigen but not on those mouse strains that were Ia-E antigen negative.

RT1.D is a gene located within the major histocompatibility complex (MHC) region of the rat genome, specifically part of the RT1 complex. RT1.D, along with its counterpart RT1.B, comprises class II MHC genes, which are key players in the adaptive immune response. These genes encode for proteins that present extracellularly derived peptides to helper T cells (CD4+ T cells), facilitating the activation and regulation of immune responses. The RT1.D gene product is analogous to human HLA-DR and mouse I-A/I-E molecules, playing an essential role in antigen presentation and immune recognition. RT1.D genes are highly polymorphic, which influences susceptibility to various diseases and are often utilized in studies involving autoimmune diseases, immune response, and transplantation immunology.
TRUSTED_SUSTAINABILITY

Especificaciones

Antígeno RT1.D
Aplicaciones Flow Cytometry
Clasificación Monoclonal
Clon OX-17
Concentración 0.1 mg/mL
Conjugado FITC
Formulación PBS with 4-5mg/mL BSA and 0.02% sodium azide
génica RT1-Db1
N.º de referencia del gen P18211
Alias de gen Db1; MHC class II RT1D beta1 chain antigen; rano class II histocompatibility antigen, D-1 beta chain; rat class I D; RT1 class II histocompatibility antigen, D-1 beta chain; RT1 class II, locus Db1; RT1-D beta; RT1-Db; RT1-Db1; RT1-Db1n
Símbolos de los genes RT1-Db1
Especie del huésped Mouse
Inmunógeno Rat spleen membrane glycoproteins depleted of Ia-A antigens.
Método de purificación Protein G
Cantidad 500 μg
Estado normativo RUO
Primario o secundario Primary
ID de gen (Entrez) 294270
Especies diana Rat
Contenido y almacenamiento Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Store in the dark.
Tipo de producto Antibody
Formulario Liquid
Isotype IgG1
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