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Invitrogen™ RON Monoclonal Antibody (1B5A9)
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Código de producto. 11355413
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Cantidad:
100 μL
Tamaño de la unidad:
100 microlitros
Código de producto. Cantidad unitSize
11355413 100 μL 100 microlitros
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Código de producto. 11355413

Marca: Invitrogen™ MA515441

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Mouse Monoclonal Antibody

MA5-15441 targets RON in indirect ELISA, WB applications and shows reactivity with Human samples. The MA5-15441 immunogen is purified recombinant fragment of human RON (aa210-320) expressed in E. Coli. MA5-15441 detects RON which has a predicted molecular weight of approximately 152kDa.

MST1R (RON) is a receptor tyrosine kinase involved in cell proliferation and motility. The protein is a membrane-spanning, disulfide-linked heterodimer, which results from cleavage of a glycosylated precursor into 35-kD (alpha) and 150-kD (beta) subunits. Ligand binding results in tyrosine phosphorylation of the beta chain. In knockout studies, MST1R/RON (-/-) mice failed to survive past the periimplantation period. The MST1R/RON gene has been mapped to 3p21, a region of frequent deletion or mutation in small cell lung and renal carcinoma, and has been implicated in the progression of several epithelial cancers. MST1R/Ron expression has been documented in many normal human tissues. ESTs have been isolated from several tissue libraries, including normal colon, mouth, prostate, and testis and cancerous colon, prostate, stomach, and uteru.
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Especificaciones

Antígeno RON
Aplicaciones ELISA, Western Blot
Clasificación Monoclonal
Clon 1B5A9
Concentración Conc. Not Determined
Conjugado Unconjugated
Formulación Ascites with 0.03% sodium azide
génica MST1R
N.º de referencia del gen Q04912
Alias de gen CD136; Cdw136; c-met-related tyrosine kinase; friend virus susceptibility 2; Fv2; Fv-2; macrophage stimulating 1 receptor; macrophage stimulating 1 receptor (c-met-related tyrosine kinase); macrophage-stimulating protein receptor; Macrophage-stimulating protein receptor alpha chain; Macrophage-stimulating protein receptor beta chain; MSP receptor; Mst1r; MST1R variant RON30; MST1R variant RON62; p185-Ron; protein tyrosine kinase 8; Protein-tyrosine kinase 8; PTK8; PTK8 protein tyrosine kinase 8; receptor protein tyrosine kinase, c-met-related; RON; RON variant E2E3; Stem cell-derived tyrosine kinase; STK
Símbolos de los genes MST1R
Especie del huésped Mouse
Inmunógeno Purified recombinant fragment of human RON (aa210-320) expressed in E. Coli.
Cantidad 100 μL
Estado normativo RUO
Primario o secundario Primary
ID de gen (Entrez) 4486
Especies diana Human
Contenido y almacenamiento Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Tipo de producto Antibody
Formulario Liquid
Isotype IgG1
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