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Invitrogen™ REA Polyclonal Antibody
Rabbit Polyclonal Antibody
Marca: Invitrogen™ PA514132
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Descripción
This antibody is predicted to react with bovine, chicken and rat based on sequence homology.
PHB2 acts as a mediator of transcriptional repression by nuclear hormone receptors via recruitment of histone deacetylases. This protein functions as an estrogen receptor (ER)-selective coregulator that potentiates the inhibitory activities of antiestrogens and represses the activity of estrogens. It competes with NCOA1 for modulation of ER transcriptional activity. It is probably involved in regulating mitochondrial respiration activity and in aging.
Especificaciones
| REA | |
| Polyclonal | |
| Unconjugated | |
| PHB2 | |
| AU044498; BAP; Bap37; Bap-37; Bcap27; BCAP37; B-cell associated protein; B-cell receptor associated protein 37; B-cell receptor-associated protein 37; B-cell receptor-associated protein BAP37; D-prohibitin; hBAP; MGC117268; p22; phb2; phb2 {ECO:0000250; PNAS-141; prohibitin 2; prohibitin-2; Rea; Repressor of estrogen receptor activity; UniProtKB:Q99623} | |
| Rabbit | |
| Antigen Affinity Chromatography, Protein A | |
| RUO | |
| 11331, 12034 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Liquid |
| Immunohistochemistry (Paraffin), Western Blot | |
| 0.5 mg/mL | |
| PBS with 0.09% sodium azide; pH 7.4 | |
| O35129, Q99623 | |
| PHB2 | |
| KLH conjugated synthetic peptide between 106-134 amino acids from human PHB2. | |
| 400 μL | |
| Primary | |
| Human, Mouse | |
| Antibody | |
| IgG |
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