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RAD51, Rat, Polyclonal Antibody, Abnova™
Rabbit polyclonal antibody raised against synthetic peptide of RAD51.
Marca: Abnova PAB24992.100uL
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Descripción
The protein encoded by this gene is a member of the RAD51 protein family. RAD51 family members are highly similar to bacterial RecA and Saccharomyces cerevisiae Rad51, and are known to be involved in the homologous recombination and repair of DNA. This protein can interact with the ssDNA-binding protein RPA and RAD52, and it is thought to play roles in homologous pairing and strand transfer of DNA. This protein is also found to interact with BRCA1 and BRCA2, which may be important for the cellular response to DNA damage. BRCA2 is shown to regulate both the intracellular localization and DNA-binding ability of this protein. Loss of these controls following BRCA2 inactivation may be a key event leading to genomic instability and tumorigenesis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Especificaciones
| RAD51 | |
| Polyclonal | |
| Unconjugated | |
| Western Blot (1:500-1:1000) Immunohistochemistry (1:50-1:200) Immunofluorescence (1:50-1:200) The optimal working dilution should be determined by the end user. | |
| RAD51 | |
| RAD51 | |
| A synthetic peptide corresponding to RAD51. | |
| 100 μL | |
| Primary | |
| RAD51 polyclonal antibody detects endogenous levels of RAD51D protein. | |
| Store at 4°C. For long term storage store at -20°C. Aliquot to avoid repeated freezing and thawing. |
| Immunohistochemistry, Western Blot | |
| 1 mg/mL | |
| Rabbit polyclonal antibody raised against synthetic peptide of RAD51. | |
| In PBS, pH 7.2 (0.05% sodium azide) | |
| BRCC5/HRAD51/HsRad51/HsT16930/RAD51A/RECA | |
| Rat | |
| Antigen affinity purification | |
| RUO | |
| 5888 | |
| Human | |
| Liquid |
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Título del producto
For Research Use Only
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