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Invitrogen™ RASD2 Polyclonal Antibody

Descripción
A suggested positive control is human colon tissue lysate. PA5-20438 can be used with blocking peptide PEP-0555.
Rhes, also known as tumor endothelial marker 2 (TEM2), is a small GTP-binding protein that is predominantly expressed in the striatal region of the brain. This protein belongs to the RASD subfamily of Ras-related GTP-binding protein superfamily and is thought to play a role in the normal development and function of the brain as mice lacking this gene showed increased anxiety levels and motor coordination deficits. Rhes was identified as TEM2 through analysis of genes whose expression was upregulated in tumor endothelium. Tumor endothelial markers are significantly up-regulated during angiogenesis and neoangiogenesis that are crucial for the growth of solid tumors. TEMs localized on the cell surface and conserved across species are of particular interest for future development of anti-angiogenic therapies.
Especificaciones
Especificaciones
| Antígeno | RASD2 |
| Aplicaciones | Immunohistochemistry, Western Blot, Immunocytochemistry |
| Clasificación | Polyclonal |
| Concentración | 1 mg/mL |
| Conjugado | Unconjugated |
| Formulación | PBS with 0.02% sodium azide |
| génica | RASD2 |
| N.º de referencia del gen | P63032, P63033, Q96D21 |
| Alias de gen | 4930526B11Rik; AU045414; GTP-binding protein Rhes; MGC:4834; Ras homolog enriched in striatum; RASD family member 2; RASD family, member 2; Rasd2; Rhes; SE6C; TEM2; TEM-2; Tumor endothelial marker 2 |
| Símbolos de los genes | RASD2 |
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Título del producto
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