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RANKL Mouse anti-Human, Clone: 3F2E1, Proteintech
Mouse Monoclonal Antibody
Marca: Proteintech 66610-1-IG-20UL
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Descripción
sRANKL is a member of the tumor necrosis factor (TNF) cytokine family which is a ligand for osteoprotegerin and functions as a key factor for osteoclast differentiation and activation. This protein was shown to be a dentritic cell survival factor and is involved in the regulation of T cell-dependent immune response. T cell activation was reported to induce expression of this gene and lead to an increase of osteoclastogenesis and bone loss. This protein was shown to activate antiapoptotic kinase AKT/PKB through a signaling complex involving SRC kinase and tumor necrosis factor receptor-associated factor (TRAF) 6, which indicated this protein may have a role in the regulation of cell apoptosis.Especificaciones
| RANKL | |
| Monoclonal | |
| 1 mg/mL | |
| PBS with 50% glycerol and 0.1% sodium azide; pH 7.3 | |
| O14788 | |
| TNFSF11 | |
| RANKL Fusion Protein Ag19975 | |
| 20 μL | |
| Primary | |
| Human | |
| Antibody | |
| IgG1 |
| Western Blot, Immunohistochemistry (Paraffin) | |
| 3F2E1 | |
| Unconjugated | |
| TNFSF11 | |
| CD254, hRANKL2, ODF, OPGL, OPTB2, Osteoprotegerin ligand, RANKL, sOdf, TNFSF11, TRANCE | |
| Mouse | |
| Protein G | |
| RUO | |
| 8600 | |
| -20°C | |
| Liquid |
Título del producto
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