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TNNI3 Rabbit anti-Human, Mouse, Rat, Polyclonal Antibody, Abnova™
Description
Troponin I (TnI), along with troponin T (TnT) and troponin C (TnC), is one of 3 subunits that form the troponin complex of the thin filaments of striated muscle. TnI is the inhibitory subunit; blocking actin-myosin interactions and thereby mediating striated muscle relaxation. The TnI subfamily contains three genes: TnI-skeletal-fast-twitch, TnI-skeletal-slow-twitch, and TnI-cardiac. This gene encodes the TnI-cardiac protein and is exclusively expressed in cardiac muscle tissues. Mutations in this gene cause familial hypertrophic cardiomyopathy type 7 (CMH7) and familial restrictive cardiomyopathy (RCM). [provided by RefSeq
Specifications
Specifications
| Antígeno | TNNI3 |
| Aplicaciones | ELISA, Immunohistochemistry (PFA fixed), Western Blot |
| Clasificación | Polyclonal |
| Concentración | 1 mg/mL |
| Conjugado | Unconjugated |
| Descripción | Rabbit polyclonal antibody raised against synthetic peptide of TNNI3. |
| Dilución | Western Blot (1:500-1:1000) Immunohistochemistry (1:50-1:100) ELISA (1:5000) The optimal working dilution should be determined by the end user. |
| Formulación | In PBS, 150mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide) |
| génica | TNNI3 |
| Alias de gen | CMD2A/CMH7/MGC116817/RCM1/TNNC1/cTnI |
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For Research Use Only
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