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SNCA Rabbit anti-Human, Mouse, Rat, Polyclonal Antibody, Abnova™
Rabbit polyclonal antibody raised against synthetic peptide of SNCA.
Marca: Abnova PAB14318.100uL
Descripción
Alpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein. Synucleins are abundantly expressed in the brain and alpha- and beta-synuclein inhibit phospholipase D2 selectively. SNCA may serve to integrate presynaptic signaling and membrane trafficking. Defects in SNCA have been implicated in the pathogenesis of Parkinson disease. SNCA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer's disease. Four alternatively spliced transcripts encoding two different isoforms have been identified for this gene. [provided by RefSeq]
Sequence: SEEGYQDYEPEAEspecificaciones
| SNCA | |
| Polyclonal | |
| Rabbit polyclonal antibody raised against synthetic peptide of SNCA. | |
| Lyophilized from PBS | |
| MGC110988/NACP/PARK1/PARK4/PD1 | |
| Rabbit | |
| 100 μL | |
| Primary | |
| Immunohistochemical and western blot analysis of human brain indicates a high level of specificity for this antiserum. | |
| Store at 4°C on dry atmosphere. After reconstitution with deionized water store at -20°C or lower. Aliquot to avoid repeated freezing and thawing. |
| Immunohistochemistry, Western Blot | |
| Unconjugated | |
| Immunohistochemistry (1:500-1:3000) Western Blot (1:500-1:3000) The optimal working dilution should be determined by the end user. | |
| SNCA | |
| SNCA | |
| A synthetic peptide (conjugated with blue carrier protein) corresponding to amino acids 129-140 of human SNCA. | |
| RUO | |
| 6622 | |
| Human, Mouse, Rat | |
| Lyophilized |
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For Research Use Only