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ERBB4 Rabbit anti-Human, Polyclonal Antibody, Abnova™
Rabbit polyclonal antibody raised against synthetic peptide of ERBB4.
Marca: Abnova PAB3039.400uL
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Descripción
This gene is a member of the Tyr protein kinase family and the epidermal growth factor receptor subfamily. It encodes a single-pass type I membrane protein with multiple cysteine rich domains, a transmembrane domain, a tyrosine kinase domain, a phosphotidylinositol-3 kinase binding site and a PDZ domain binding motif. The protein binds to and is activated by neuregulins and other factors and induces a variety of cellular responses including mitogenesis and differentiation. Multiple proteolytic events allow for the release of a cytoplasmic fragment and an extracellular fragment. Mutations in this gene have been associated with cancer. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized. [provided by RefSeq
Especificaciones
| ERBB4 | |
| Polyclonal | |
| Rabbit polyclonal antibody raised against synthetic peptide of ERBB4. | |
| In PBS (0.09% sodium azide) | |
| Q15303 | |
| ERBB4 | |
| A synthetic peptide (conjugated with KLH) corresponding to C-terminus of human ERBB4. | |
| 400 μL | |
| Primary | |
| Human | |
| Liquid |
| ELISA, Immunohistochemistry, Western Blot | |
| Unconjugated | |
| Western Blot (1:1000) Immunohistochemistry (1:50-100) The optimal working dilution should be determined by the end user. | |
| ERBB4 | |
| HER4/MGC138404/p180erbB4 | |
| Rabbit | |
| Protein G purification | |
| RUO | |
| 2066 | |
| Store at 4°C. For long term storage store at -20°C. Aliquot to avoid repeated freezing and thawing. |
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For Research Use Only
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