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BLNK Rabbit anti-Human, Mouse, Polyclonal Antibody, Abnova™
Rabbit polyclonal antibody raised against partial recombinant BLNK.
Marca: Abnova PAB13541.100ug
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Descripción
This gene encodes a cytoplasmic linker or adaptor protein that plays a critical role in B cell development. This protein bridges B cell receptor-associated kinase activation with downstream signaling pathways, thereby affecting various biological functions. The phosphorylation of five tyrosine residues is necessary for this protein to nucleate distinct signaling effectors following B cell receptor activation. Mutations in this gene cause hypoglobulinemia and absent B cells, a disease in which the pro- to pre-B-cell transition is developmentally blocked. Deficiency in this protein has also been shown in some cases of pre-B acute lymphoblastic leukemia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Especificaciones
| BLNK | |
| Polyclonal | |
| Rabbit polyclonal antibody raised against partial recombinant BLNK. | |
| In PBS, pH 7.4 (0.09% sodium azide) | |
| BASH/BLNK-S/LY57/MGC111051/SLP-65/SLP65 | |
| Rabbit | |
| 100 μg | |
| Primary | |
| This antibody reacts with mouse BLNK, a cytosolic adaptor protein identified as two phosphoproteins migrating at 68 and 70 KDa in SDS PAGE (alternatively spliced forms of human SLP65). | |
| Store at 4°C. Do not freeze. Aliquot to avoid repeated freezing and thawing. |
| Western Blot | |
| Unconjugated | |
| The optimal working dilution should be determined by the end user. | |
| BLNK | |
| BLNK | |
| Recombinant protein corresponding to amino acids 171-356 of human BLNK. | |
| RUO | |
| 29760 | |
| Human, Mouse | |
| Liquid |
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Título del producto
For Research Use Only
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