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BAX (phospho T167), Rabbit anti-Human, Polyclonal Antibody, Abnova™

Rabbit polyclonal antibody raised against synthetic phosphopeptide of human BAX.

Marca:  Abnova PAB29272.100uL

Código de producto. 16204270

  • 403.00€ / 100 microlitros

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Descripción

Descripción

The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein forms a heterodimer with BCL2, and functions as an apoptotic activator. This protein is reported to interact with, and increase the opening of, the mitochondrial voltage-dependent anion channel (VDAC), which leads to the loss in membrane potential and the release of cytochrome c. The expression of this gene is regulated by the tumor suppressor P53 and has been shown to be involved in P53-mediated apoptosis. Multiple alternatively spliced transcript variants, which encode different isoforms, have been reported for this gene. [provided by RefSeq

Especificaciones

Especificaciones

BAX
Polyclonal
Rabbit polyclonal antibody raised against synthetic phosphopeptide of human BAX.
In PBS (without mg2+ and Ca2+), 150mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide)
Q07812
BAX
Synthetic phosphopeptide (conjugated with KLH) corresponding to residues surrounding T167 of human BAX.
100 μL
Primary
BAX (phospho T167) polyclonal antibody detects endogenous levels of human BAX only when phosphorylated at threonine 167.
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
Immunofluorescence
Unconjugated
Immunofluorescence (1:100∼1:200) The optimal working dilution should be determined by the end user.
BAX
BCL2L4
Rabbit
Affinity Chromatography
RUO
581
Human
Liquid
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