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AGT Rabbit anti-Human, Monkey, Polyclonal Antibody, Abnova™
Rabbit polyclonal antibody raised against synthetic peptide of AGT.
Marca: Abnova PAB27759.50ug
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Descripción
The protein encoded by this gene, pre-angiotensinogen or angiotensinogen precursor, is expressed in the liver and is cleaved by the enzyme renin in response to lowered blood pressure. The resulting product, angiotensin I, is then cleaved by angiotensin converting enzyme (ACE) to generate the physiologically active enzyme angiotensin II. The protein is involved in maintaining blood pressure and in the pathogenesis of essential hypertension and preeclampsia. Mutations in this gene are associated with susceptibility to essential hypertension, and can cause renal tubular dysgenesis, a severe disorder of renal tubular development. Defects in this gene have also been associated with non-familial structural atrial fibrillation, and inflammatory bowel disease. [provided by RefSeq
Especificaciones
| AGT | |
| Polyclonal | |
| Rabbit polyclonal antibody raised against synthetic peptide of AGT. | |
| In PBS (0.09% sodium azide) | |
| P01019 | |
| AGT | |
| A synthetic peptide corresponding to 13 amino acid at internal region of human AGT. | |
| 50 μg | |
| Primary | |
| BLAST analysis of the peptide immunogen showed no homology with other human proteins. | |
| Store at 4°C. For long term storage store at -80°C. Aliquot to avoid repeated freezing and thawing. |
| Immunohistochemistry (PFA fixed) | |
| Unconjugated | |
| Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (2.5-5 ug/mL) The optimal working dilution should be determined by the end user. | |
| AGT | |
| ANHU/FLJ92595/FLJ97926/SERPINA8 | |
| Rabbit | |
| Immunoaffinity chromatography | |
| RUO | |
| 183 | |
| Human, Monkey | |
| Liquid |
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Título del producto
For Research Use Only
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