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ADAMTS4 Rabbit anti-Dog, Horse, Human, Monkey, Polyclonal Antibody, Abnova™
Rabbit polyclonal antibody raised against synthetic peptide of ADAMTS4.
Marca: Abnova PAB16218.50ug
Descripción
This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The enzyme encoded by this gene lacks a C-terminal TS motif. It is responsible for the degradation of aggrecan, a major proteoglycan of cartilage, and brevican, a brain-specific extracellular matrix protein. The cleavage of aggrecan and brevican suggests key roles of this enzyme in arthritic disease and in the central nervous system, potentially, in the progression of glioma. [provided by RefSeq
Especificaciones
| ADAMTS4 | |
| Polyclonal | |
| Rabbit polyclonal antibody raised against synthetic peptide of ADAMTS4. | |
| In PBS (0.09% sodium azide) | |
| O75173 | |
| ADAMTS4 | |
| A synthetic peptide (conjugated with KLH) corresponding to human ADAMTS4. | |
| 50 μg | |
| Primary | |
| internal domain of human . | |
| Store at 4°C. For long term storage store at -20°C. Aliquot to avoid repeated freezing and thawing. |
| Immunohistochemistry (PFA fixed) | |
| Unconjugated | |
| Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (2.6 ug/mL) The optimal working dilution should be determined by the end user. | |
| ADAMTS4 | |
| ADAMTS-2/ADAMTS-4/ADMP-1/KIAA0688 | |
| Rabbit | |
| Immunoaffinity purification | |
| RUO | |
| 9507 | |
| Canine, Equine, Human, Monkey | |
| Liquid |
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