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Invitrogen™ PTPRN2 Polyclonal Antibody

Descripción
Antibody detects endogenous levels of total PTP IA-2beta.
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and a single intracellular catalytic domain, and thus represents a receptor-type PTP. The catalytic domain of this PTP is most closely related to PTPRN/IA-2beta. This PTP and PTPRN are both found to be major autoantigens associated with insulin-dependent diabetes mellitus. Three alternatively spliced transcript variants of this gene, which encode distinct proteins, have been reported.
Especificaciones
Especificaciones
| Antígeno | PTPRN2 |
| Aplicaciones | Western Blot, Immunocytochemistry |
| Clasificación | Polyclonal |
| Concentración | 1 mg/mL |
| Conjugado | Unconjugated |
| Formulación | PBS with 50% glycerol and 0.02% sodium azide; pH 7.4 |
| génica | PTPRN2 |
| N.º de referencia del gen | P80560, Q63475, Q92932 |
| Alias de gen | 4930425H11Rik; EC 3.1.3.48; IA-2 beta; IA2beta; IA-2beta; IA-2beta60; IA-2beta64; IA-2beta71; IAR; IAR/receptor-like protein-tyrosine phosphatase; ICAAR; Islet cell autoantigen-related protein; KIAA0387; mKIAA0387; phogrin; Phol; protein tyrosine phosphatase receptor pi; protein tyrosine phosphatase receptor-type N polypeptide 2; protein tyrosine phosphatase, receptor type N2; protein tyrosine phosphatase, receptor type, N polypeptide 2; protein tyrosine phosphatase, receptor-type, N polypeptide 2; protein tyrosine phosphatase-NP; PTP IA-2beta; PTP NE-6; PTPNE6; PTP-NP; PTPRN2; PTPRP; Receptor-type tyrosine-protein phosphatase N2; R-PTP-N2; tyrosine phosphatase IA-2 beta |
| Símbolos de los genes | PTPRN2 |
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Título del producto
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