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Invitrogen™ PSMD10 Polyclonal Antibody
Descripción
Recommended positive controls: 293T, A431, H1299, HeLa, HepG2, Molt-4, Raji. Predicted reactivity: Mouse (95%), Rat (94%), Chicken (81%), Rhesus Monkey (100%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a non-ATPase subunit of the 19S regulator. Two transcripts encoding different isoforms have been described. Pseudogenes have been identified on chromosomes 3 and 20.
Especificaciones
Especificaciones
| Antígeno | PSMD10 |
| Aplicaciones | Western Blot, Immunocytochemistry |
| Clasificación | Polyclonal |
| Concentración | 0.26 mg/mL |
| Conjugado | Unconjugated |
| Formulación | 0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7 |
| génica | PSMD10 |
| N.º de referencia del gen | O75832 |
| Alias de gen | 26S proteasome non-ATPase regulatory subunit 10; 26S proteasome regulatory subunit p28; ankyrin repeat protein; AW554874; dJ889N15.2; Gankyrin; hepatocellular carcinoma-associated protein p28-II; p28; p28(GANK); p28Gank; proteasome (prosome, macropain) 26S subunit, non-ATPase, 10; proteasome 26S subunit, non-ATPase 10; proteasome subunit p28; proteosome (prosome, macropain) 26S subunit, non-ATPase, 10; proteosome subunit p28; PSMD10 |
| Símbolos de los genes | PSMD10 |
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Título del producto
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