Protein Gene Product 9.5 (PGP9.5) Rabbit Polyclonal Antibody, Epredia™

Protein gene product (PGP9.5) is a neuron specific protein, structurally and immunologically distinct from neuron specific enolase. The protein, which has a molecular weight of 27kDa, was first identified by high resolution two dimensional PAGE. Standard immunohistochemical techniques have demonstrated the presence of PGP9.5 in neurons and nerve fibres at all levels of the central and peripheral nervous system, in many neuroendocrine cells, in segments of the renal tubules, in spermatogonia and Leydig cells of the testis, in ova and in some cells of both the pregnant and non-pregnant corpus luteum. This antibody is of value as a marker for neurons and may be of particular use in the study of ubiquitinated cellular inclusions characteristic of several chronic human neurodegenerative diseases. This antibody is suitable for staining of formalin-fixed, paraffin-embedded tissues.

Host Species: Rabbit

Isotype: IgG

Species Reactivity: Human. Others not tested.

Epitope: Not known

Immunogen: Recombinant full-length human PGP9.5 protein

Molecular Weight: 9.5kDa

Positive Control: Pancreas and small intestine

Cellular Localization: Cytoplasmic and nuclear

Recommended for:

• Immunohistochemistry (Formalin/paraffin)