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Invitrogen™ PRMT5 Polyclonal Antibody
Rabbit Polyclonal Antibody
Marca: Invitrogen™ PA530383
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Descripción
Recommended positive controls: 293T, A431, Jurkat, Raji. Predicted reactivity: Mouse (98%), Rat (98%), Zebrafish (85%), Japanese Medaka (86%), Xenopus laevis (91%), Pig (100%), Rhesus Monkey (100%), Chimpanzee (99%), Bovine (98%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
PRMT5 (protein arginine N-methyltransferase 5) is an arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA), with a preference for the formation of MMA. PRMT5 specifically mediates the symmetrical dimethylation of arginine residues in the small nuclear ribonucleoproteins Sm D1 and Sm D3; such methylation is required for the assembly and biogenesis of snRNP core particles.
Especificaciones
| PRMT5 | |
| Polyclonal | |
| Unconjugated | |
| PRMT5 | |
| 72 kDa ICln-binding protein; EC 2.1.1.125; histone-arginine N-methyltransferase PRMT5; HMT1 hnRNP methyltransferase-like 5; HRMT1L5; hypothetical protein; I79_013398; IBP72; Jak-binding protein 1; JBP1; PRMT5; protein arginine methyltransferase 5; protein arginine N-methyltransferase 5; Protein arginine N-methyltransferase 5, N-terminally processed; protein arginine N-methyltransferase 5-like; shk1 kinase-binding protein 1 homolog; Skb1; SKB1 homolog; SKB1Hs | |
| Rabbit | |
| Antigen affinity chromatography | |
| RUO | |
| 10419, 27374 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Liquid |
| Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry | |
| 0.49 mg/mL | |
| PBS with 1% BSA, 20% glycerol; pH 7 | |
| O14744, Q8CIG8 | |
| PRMT5 | |
| Recombinant protein encompassing a sequence within the center region of human PRMT5. The exact sequence is proprietary. | |
| 100 μL | |
| Primary | |
| Human, Mouse | |
| Antibody | |
| IgG |
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