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Invitrogen™ PRAS40 Monoclonal Antibody (73P21)
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Product Code. 10008252
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Cantidad:
100 μg
Unit Size:
cada uno
Product Code. Cantidad unitSize
10008252 100 μg cada uno
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Product Code. 10008252

Brand: Invitrogen™ AHO1031

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Description

Mouse Monoclonal Antibody

PRAS40 Monoclonal Antibody for Western Blot, IHC (P), ICC/IF, IP

The Akt signaling pathway contributes to the regulation of apoptosis after a variety of cell death signals. AKT1S1, also known as PRAS40, is a proline-rich substrate of the kinase AKT1 and is thought to play a role in neuroprotection mediated by nerve growth factor (NGF) after transient focal cerebral ischemia. AKT1S1 is also a substrate and potential regulator of mammalian target of rapamycin (mTOR), a serine/threonine kinase that regulates cell growth and cell cycle, and a negative regulator of autophagy. Treatment with the insulin-like growth factor-1 (IGF1) can induce the phosphorylation of AKT1S1 via the PI3K/AKT signaling pathway in PC12 cells.
TRUSTED_SUSTAINABILITY

Specifications

Antígeno PRAS40
Aplicaciones Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot, Immunocytochemistry
Clasificación Monoclonal
Clon 73P21
Concentración 0.5 mg/mL
Conjugado Unconjugated
Formulación PBS with 1% BSA and 0.1% sodium azide
génica AKT1S1
N.º de referencia del gen Q96B36
Alias de gen 1110012J22Rik; 40 kDa proline-rich AKT substrate; AI227026; AKT1 substrate 1; AKT1 substrate 1 (proline rich); AKT1 substrate 1 (proline-rich); akt1s1; Lobe; Lobel; OTTHUMP00000196756; OTTHUMP00000196760; PKB/Akt substrate 40; Pras; PRAS40; Proline-rich AKT substrate; proline-rich AKT1 substrate 1
Símbolos de los genes AKT1S1
Especie del huésped Mouse
Inmunógeno Recombinant full length human PRAS40 expressed in E. coli.
Método de purificación Purified
Cantidad 100 μg
Estado normativo RUO
Primario o secundario Primary
ID de gen (Entrez) 84335
Especies diana Human
Contenido y almacenamiento -20°C
Tipo de producto Antibody
Formulario Liquid
Isotype IgG1 κ
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