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Description
This gene encodes a member of the phospholipase C family, which catalyze the hydrolysis of phosphatidylinositol 4, 5-bisphosphate to generate the second messengers diacylglycerol and inositol 1, 4, 5-trisphosphate (IP3). Diacylglycerol and IP3 mediate a variety of cellular responses to extracellular stimuli by inducing protein kinase C and increasing cytosolic Ca(2+) concentrations. This enzyme localizes to the plasma membrane and requires calcium for activation. Its activity is inhibited by spermine, sphingosine, and several phospholipids.
Specifications
Specifications
| Antígeno | PLCD3 |
| Aplicaciones | Western Blot |
| Clasificación | Polyclonal |
| Concentración | 0.15 mg/mL |
| Conjugado | Unconjugated |
| Formulación | PBS with 50% glycerol and 0.1% sodium azide; pH 7.3 |
| génica | PLCD3 |
| N.º de referencia del gen | Q8K2J0, Q8N3E9 |
| Alias de gen | KIAA1964, Phospholipase C delta 3, phospholipase C, delta 3, PLC delta 3, PLCD3 |
| Símbolos de los genes | Plcd3 |
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