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Invitrogen™ Phospho-Talin (Ser425) Polyclonal Antibody
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Código de producto. 17816798
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Cantidad:
100 μL
Unit Size:
100 microlitros
Product Code. Cantidad unitSize
17816798 100 μL 100 microlitros
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Product Code. 17816798

Brand: Invitrogen™ PA5143776

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Rabbit Polyclonal Antibody

The antibody detects a 240 kDa* protein corresponding to the molecular mass of Talin on SDS-PAGE immunoblots of human A431, rat PC12, and rabbit fibroblast cells treated with Calyculin A, but is not observed after lambda phosphatase treatment.

Talin, a multifunctional constituent of cell-substratum attachment sites, is a high molecular weight protein (225-235 kDa) found in variety of tissues and cell types. It is localized at a subset of adherens junctions, specialized cell-cell and cell-matrix associations that are characterized by the presence of filamentous actin at the cytoplasmic face of the junctional complex. In cultured cells, talin is absent from cell-cell junctions and found predominantly at adhesion plaques and in fibrillar streaks underlying cell surface fibronectin. Talin interacts with at least two other proteins that are localized at adhesion plaques, vinculin and integrin.
TRUSTED_SUSTAINABILITY

Specifications

Antígeno Phospho-Talin (Ser425)
Aplicaciones Western Blot, Immunocytochemistry
Clasificación Polyclonal
Concentración 1 mg/mL
Conjugado Unconjugated
Formulación PBS with 1mg/mL BSA, 50% glycerol and 0.05% sodium azide
génica TLN2
N.º de referencia del gen P26039, Q71LX4, Q9Y490, Q9Y4G6
Alias de gen 5730421P04Rik; AI507121; AI787438; AL118320; ILWEQ; KIAA0320; KIAA1027; mKIAA0320; RGD1565416; talin 1; talin 2; talin-1; Talin-2; TLN; Tln1; Tln2
Símbolos de los genes TLN1, TLN2
Especie del huésped Rabbit
Inmunógeno Phospho-Talin (Ser-425) synthetic peptide (coupled to carrier protein) corresponding to amino acids surrounding Ser-425 in human Talin 1. This sequence is conserved in rat, mouse, and chicken Talin 1, as well as in Talin 2 (Ser-428).
Método de purificación Antigen affinity chromatography
Cantidad 100 μL
Estado normativo RUO
Primario o secundario Primary
ID de gen (Entrez) 21894, 313494, 315776, 70549, 7094, 83660
Especies diana Human, Mouse, Rat
Contenido y almacenamiento -20°C, Avoid Freeze/Thaw Cycles
Tipo de producto Antibody
Formulario Liquid
Isotype IgG
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