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Invitrogen™ Phospho-STAT6 (Thr645) Polyclonal Antibody
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Código de producto. 15554001
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Cantidad:
100 μL
Tamaño de la unidad:
100 microlitros
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Código de producto. Cantidad unitSize
15554001 100 μL 100 microlitros
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Product Code. 15554001 Supplier Invitrogen™ Supplier No. PA536690

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Description

Rabbit Polyclonal Antibody

This antibody detects endogenous protein at a molecular weight of 94 kDa. Purity is >95% by SDS-PAGE.

STAT6 protein is a transcription factor activated by cytokines, particularly interleukin-4 and IL13. (Stat6-/-) were found to be deficient in IL-4-mediated functions including Th2 helper T-cell differentiation, expression of cell surface markers, T-cell proliferation, immunoglobulin class switching to IgE, and partial loss of IL-4 mediated proliferation. STAT6 mRNA has been detected in peripheral blood lymphocytes, colon, intestine, ovary, prostate, thymus, spleen, kidney, liver, lung and placenta. STAT6 is critically involved in Th2 immune response. STAT6 is crucial for IL-4-mediated biological responses, and naturally in two isoforms: STAT6a and STAT6c.
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Specifications

Antígeno Phospho-STAT6 (Thr645)
Aplicaciones Immunohistochemistry (Paraffin), Immunoprecipitation
Clasificación Polyclonal
Concentración 1 mg/mL
Conjugado Unconjugated
Formulación PBS with 50% glycerol and 0.02% sodium azide; pH 7.2
génica STAT6
N.º de referencia del gen P42226, P52633
Alias de gen 12S1644; D12S1644; IL4 STAT; IL-4 Stat; IL-4-STAT; signal transducer and activator of transcription 6; signal transducer and activator of transcription 6, interleukin-4 induced; signal transducer and transcription activator 6; STAT; STAT, interleukin4-induced; Stat6; STAT-6; STAT6B; STAT6C; transcription factor IL-4 STAT
Símbolos de los genes STAT6
Especie del huésped Rabbit
Inmunógeno Synthetic phosphopeptide derived from human Stat6 around the phosphorylation site of Threonine 645.
Método de purificación Antigen affinity chromatography
Cantidad 100 μL
Estado normativo RUO
Primario o secundario Primary
ID de gen (Entrez) 20852, 362896, 6778
Especies diana Human, Mouse, Rat
Contenido y almacenamiento Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Tipo de producto Antibody
Formulario Liquid
Isotype IgG
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