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Invitrogen™ Phospho-RelB (Ser552) Polyclonal Antibody
Rabbit Polyclonal Antibody
Marca: Invitrogen™ PA536837
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Descripción
This antibody detects endogenous protein at a molecular weight of 70 kDa. Purity is >95% by SDS-PAGE.
The NFkB transcription factor was originally identified as a protein complex consisting of a DNA-binding subunit and an associated protein. The DNAbinding subunit is functionally related to c-Rel p75 and Rel B p68. The p50 subunit was initially believed to be a functionally unique protein derived from the amino-terminus of a precursor designated p105. A second protein designated p52 (previously referred to as p49) has been identified that can act as an alternative NFkB subunit. Rel B does not bind with high affinity to NFkB sites, but heterodimers between Rel B and p50 bind with an affinity comparable to that of p50 NFkB homodimers. However, Rel B/p50 heterodimers, in contrast to NFkB heterodimers, transactivates transcription of promotors containing kB binding sites.
Especificaciones
| Phospho-RelB (Ser552) | |
| Polyclonal | |
| Unconjugated | |
| RELB | |
| avian reticuloendotheliosis viral (v-rel) oncogene related B; IREL; I-REL; OTTHUMP00000221313; rel b; RELB; REL-B; RELB proto-oncogene, NF-kB subunit; shep; transcription factor RelB; v-rel avian reticuloendotheliosis viral oncogene homolog B; v-rel avian reticuloendotheliosis viral oncogene homolog B (nuclear factor of kappa light polypeptide gene enhancer in B-cells 3); v-rel reticuloen; v-rel reticuloendotheliosis viral oncogene homolog B; v-rel reticuloendotheliosis viral oncogene homolog B, nuclear factor of kappa light polypeptide gene enhancer in B-cells 3 | |
| Rabbit | |
| Antigen affinity chromatography | |
| RUO | |
| 100360982, 19698, 5971 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Liquid |
| Immunohistochemistry (Paraffin), Western Blot | |
| 1 mg/mL | |
| PBS with 0.05% sodium azide; pH 7.2 | |
| Q01201, Q04863 | |
| RELB | |
| Synthetic phosphopeptide derived from human Rel B around the phosphorylation site of Serine 552. | |
| 100 μL | |
| Primary | |
| Human, Mouse, Rat | |
| Antibody | |
| IgG |
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